Results 41 to 50 of about 8,180 (214)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Novel hybrid minimal surface-based lattice materials

open access: yesMaterials & Design
The sheet-based triply periodic minimal surface (TPMS) architecture exhibits effective properties below the stiffness Hashin-Shtrikman upper bound and the strength Suquet upper bound (SU). However, some plate-based architectures have achieved these upper
Chukwugozie J. Ejeh   +2 more
doaj   +1 more source

On the minimal surfaces of Riemann

open access: yesCommentarii Mathematici Helvetici, 1992
Let \(\gamma_ 1\), \(\gamma_ 2\) be plane Jordan curves in horizontal planes \(P_ 1\), \(P_ 2\) of \(\mathbb{R}^ 3\). It is known, under simple conditions on \(\gamma_ 1\) and \(\gamma_ 2\), that they bound a least area minimal annulus between \(P_ 1\) and \(P_ 2\). \textit{W. H. Meeks III} and \textit{R. White} [Bull. Am. Math. Soc., New Ser.
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Biharmonic Maps and Laguerre Minimal Surfaces

open access: yesAbstract and Applied Analysis, 2013
A Laguerre surface is known to be minimal if and only if its corresponding isotropic map is biharmonic. For every Laguerre surface Φ is its associated surface Ψ=1+u2Φ, where u lies in the unit disk.
Yusuf Abu Muhanna, Rosihan M. Ali
doaj   +1 more source

Applications of Quaternionic Holomorphic Geometry to minimal surfaces

open access: yesComplex Manifolds, 2016
In this paper we give a survey of methods of Quaternionic Holomorphic Geometry and of applications of the theory to minimal surfaces. We discuss recent developments in minimal surface theory using integrable systems.
Leschke K., Moriya K.
doaj   +1 more source

The Existence of rG Family and tG Family, and Their Geometric Invariants

open access: yesMathematics, 2020
In the 1990s, physicists constructed two one-parameter families of compact oriented embedded minimal surfaces in flat three-tori by using symmetries of space groups, called the rG family and tG family.
Norio Ejiri, Toshihiro Shoda
doaj   +1 more source

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