Results 121 to 130 of about 9,844,505 (300)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Surfaces of Revolution with Constant Mean Curvature in Galilean 3-Space
MathematicsRevolution surfaces with zero mean curvature in the Galilean 3-space have been extensively studied in the literature. However, revolution surfaces with non-zero constant mean curvature in this geometric setting have not yet been investigated in a ...
İsmet Gölgeleyen +2 more
doaj +1 more source
Crashworthiness Design of Thin-Walled Tubes Reinforced by Triply Periodic Minimal Surfaces. [PDF]
3D Print Addit Manuf, 2021 Jiang Y, Wang S, Wang H, Li B, Hou W.
europepmc +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Minimal Curves on Ruled Surfaces Generated by Legendre Curves
Journal of New TheoryIn this paper, we study the conditions under which Legendre curves on ruled surfaces are classified as minimal loci. By investigating the scenario where the directive curve is a binormal vector, we establish the criteria for these curves to have minimal ...
Yusuf Yaylı, İsmet Gölgeleyen
doaj +1 more source
A Property of Minimal Surfaces [PDF]
Proceedings of the National Academy of Sciences, 1953 openaire +3 more sources
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Triply Periodic Minimal Surfaces Mullite Structures for Humidity Detection
ChemosensorsThree-dimensional-printed complex mullite structures based on triply periodic minimal surfaces (TPMSs, namely, Schwartz and Gyroid) with two different thicknesses (Schwartz 1 and Gyroid 1–4 mm, Schwartz 2 and Gyroid 2–6 mm) were fabricated and tested as ...
Yurii Milovanov +4 more
doaj +1 more source
A multiscale optimisation method for bone growth scaffolds based on triply periodic minimal surfaces. [PDF]
Biomech Model Mechanobiol, 2021 Lehder EF +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source