Results 111 to 120 of about 2,059,946 (289)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Minimal surfaces with symmetries

open access: yesProceedings of the London Mathematical Society
AbstractLet be a finite group acting on a connected open Riemann surface by holomorphic automorphisms and acting on a Euclidean space by orthogonal transformations. We identify a necessary and sufficient condition for the existence of a ‐equivariant conformal minimal immersion .
openaire   +6 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Geodesic Groups of Minimal Surfaces

open access: yes, 1958
In a previous paper (6) we have studied those minimal surfaces which admit geodesic mappings without isometries or similarities on another, not necessarily minimal, surface.
H. G. Helfenstein
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Constant angle surfaces in product spaces. [PDF]

open access: yes
53B25;
Dillen, Franki, Kowalczyk, Daniel
core  

Hole-filling techniques by using minimal energy surfaces

open access: yesBulletin of Computational Applied Mathematics, 2016
In the last few years, several techniques to fill holes of a given surface by means of minimal energy surfaces have been proposed. In all cases, the filling patches are obtained by minimizing an `energy functional' defined in a vector space of spline ...
Miguel Angel Fortes E.
doaj  

A Family of Minimal Surfaces and Univalent Planar Harmonic Mappings

open access: yesAbstract and Applied Analysis, 2014
We present a two-parameter family of minimal surfaces constructed by lifting a family of planar harmonic mappings. In the process, we use the Clunie and Sheil-Small shear construction for planar harmonic mappings convex in one direction.
Michael Dorff, Stacey Muir
doaj   +1 more source

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