Results 201 to 210 of about 224,088 (359)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

ICH GCP E6 has arrived: Are we ready? [PDF]

Perspect Clin Res
Davis S.
europepmc   +1 more source

Minimal contact psychotherapy reduces the risk of major depression in people with subthreshold depression [PDF]

, 2005
David Kennedy, D. R. Sherazi
openalex   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Yeast Stress Response to Synthetic Constructs. [PDF]

ACS Synth Biol
Tartik M.
europepmc   +1 more source

Less is More: Perception as a fun way to Rich Minimalism. [PDF]

Iperception, 2022
Carbon CC, Utz S, Hesslinger VM.
europepmc   +1 more source

Hale and Wright on the Metaontology of Neo-Fregeanism [PDF]

, 2016
Eklund, Matti
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

All three coronary arteries and a separate conus branch arising from the right sinus of Valsalva in an octogenarian with an acute myocardial infarction: a case report. [PDF]

Eur Heart J Case Rep
Kovacic M, Ostricki B, Ostricki M, Cvetko TT, Borovac JA.   +4 more
europepmc   +1 more source