Habituation of auditory startle reflex is a new sign of minimally conscious state. [PDF]
Brain, 2020 Disorders of consciousness are challenging to diagnose. Hermann et al. identify a new clinical sign, the habituation of auditory startle reflex, which indexes the activity of a fronto-parietal network and predicts improved consciousness at 6 months.
Hermann B +14 more
europepmc +4 more sources
Efficacy of Transcranial Direct Current Stimulation Over Dorsolateral Prefrontal Cortex in Patients With Minimally Conscious State. [PDF]
Front Neurol, 2022 Background The treatment of patients in a minimally conscious state (MCS) remains challenging. Transcranial direct current stimulation (tDCS) is a non-invasive therapeutic method in treating neurologic diseases by regulating the cortical excitability ...
Peng Y +10 more
europepmc +3 more sources
Is Animal-Assisted Therapy for Minimally Conscious State Beneficial? A Case Study [PDF]
Frontiers in Psychiatry, 2020 ObjectiveThe goal of this single case study was to qualitatively investigate the effects of animal-assisted therapy in a patient in a minimally conscious state.MethodWe present a 28-year-old female patient in a minimally conscious state following ...
Jacqueline P. Boitier +7 more
doaj +3 more sources
Outcome Prediction in Unresponsive Wakefulness Syndrome and Minimally Conscious State by Non-linear Dynamic Analysis of the EEG. [PDF]
Front Neurol, 2021 Objectives: This study aimed to investigate the role of non-linear dynamic analysis (NDA) of the electroencephalogram (EEG) in predicting patient outcome in unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS).
Liu B +7 more
europepmc +4 more sources
Changes in cerebral metabolism in patients with a minimally conscious state responding to zolpidem [PDF]
Frontiers in Human Neuroscience, 2014 Background: Zolpidem, a short-acting nonbenzodiazepine GABA agonist hypnotic, has been shown to induce paradoxical responses in some patients with disorders of consciousness, leading to recovery of arousal and cognitive abilities.
Camille eChatelle +10 more
doaj +6 more sources
Influence of Bone Marrow-Derived Mesenchymal Stem Cell Therapy on Oxidative Stress Intensity in Minimally Conscious State Patients. [PDF]
J Clin Med, 2020 Neurological disorders, including minimally conscious state (MCS), may be associated with the presence of high concentrations of reactive oxygen species within the central nervous system.
Jezierska-Wozniak K +5 more
europepmc +4 more sources
Corrigendum: Is the “Minimally Conscious State” Patient Minimally Self-Aware? [PDF]
Frontiers in Psychology, 2020 Constantinos Picolas +1 more
doaj +4 more sources
Prevalence of the Minimally Conscious State Among Institutionalized Patients in the Netherlands: A Nationwide Study. [PDF]
Neurology, 2023 Background and Objectives The minimally conscious state (MCS) is a prolonged disorder of consciousness (pDoC) and one of the most severe outcomes of acquired brain injury. Prevalence data are scarce.
Overbeek BUH +4 more
europepmc +2 more sources
Disturbed functional connectivity and topological properties of the frontal lobe in minimally conscious state based on resting-state fNIRS. [PDF]
Front Neurosci, 2023 Background Patients in minimally conscious state (MCS) exist measurable evidence of consciousness. The frontal lobe is a crucial part of the brain that encodes abstract information and is closely related to the conscious state.
Chen H +10 more
europepmc +2 more sources
Deep brain stimulation improves electroencephalogram functional connectivity of patients with minimally conscious state. [PDF]
CNS Neurosci Ther, 2023 Deep brain stimulation (DBS) is a potential neuromodulatory therapy that enhances recovery from disorders of consciousness, especially minimally conscious state (MCS).
Dang Y +6 more
europepmc +2 more sources