Results 161 to 170 of about 2,396,405 (255)

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo   +4 more
wiley   +1 more source

Regenerative Peripheral Nerve Interface (RPNI) Surgery for Naturalistic Prosthetic Control

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Loss of limb function remains a significant public health challenge affecting millions of people worldwide, causing high rates of disability, unemployment, and chronic pain. Current neuroprosthetic devices are limited by unintuitive control and poor long‐term embodiment.
Ahneesh J. Mohanty   +7 more
wiley   +1 more source

Resident Training in Minimally Invasive Spine Surgery: A Scoping Review. [PDF]

open access: yesBrain Sci
Oblich MC   +7 more
europepmc   +1 more source

Factors Impacting Continuation of Onabotulinum Toxin Therapy for Idiopathic and Neurogenic Urgency Urinary Incontinence

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Introduction We investigated demographic, diagnostic, and socioeconomic variables associated with continuation and discontinuation of onabotulinum toxin (BTX) therapy in adult patients treated for idiopathic and neurogenic urgency urinary incontinence (UUI).
Zhina Sadeghi   +10 more
wiley   +1 more source

Feasibility of High-Fidelity Simulator Models for Minimally Invasive Spine Surgery in a Resource-Limited Setting: Experience From East Africa. [PDF]

open access: yesJ Am Acad Orthop Surg Glob Res Rev, 2023
Balogun SA   +10 more
europepmc   +1 more source

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

open access: yesNeuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang   +6 more
wiley   +1 more source

How Loud is Minimally Invasive Spine Surgery? Identifying Intraoperative Risk of Hearing Loss. [PDF]

open access: yesGlobal Spine J
Ehrlich AM   +12 more
europepmc   +1 more source

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