Results 81 to 90 of about 213,568 (263)

A Derivative Method for Minimising Total Cost in Heat Exchanger Networks through Optimal Area Allocation

Chemical Engineering Transactions, 2013
This paper presents a novel Cost Derivative Method (CDM) for finding the optimal area allocation for a defined Heat Exchanger Network (HEN) structure and stream data, without any stream splits to achieve minimum total cost. Using the Pinch Design Method (
T.G. Walmsley, M.R.W. Walmsley, A.S. Morrison, M.J. Atkins, J.R. Neale   +4 more
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali, Waqar Ahmed Cheema, Fiza Nisar, Muhammad Shamoon, Sameen Sarfaraz, Ahmad Butt, Muhammad Abdullah Ali, Armaghana Abdullah, Muhammad Asad Shabbir, Muhammad Talha, Hammad Azam, Aimen Anwaar Pannun, Usama Saleem, Anousha Tanveer, Mukesh Sharma   +14 more
wiley   +1 more source

Minimum cost noncrossing flow problem on layered networks

Discrete Applied Mathematics, 2019
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
I. Kuban Altinel, Necati Aras, Zeynep Suvak, Z. Caner Taskin   +3 more
openaire   +3 more sources

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Custom Bus optimization of docking stations based on partition path selection

Advances in Mechanical Engineering, 2017
The Custom Bus has advantages on punctuality, direct arrival, and economic benefits. It has a good effect on attracting passengers from private cars commuting in city. Due to the unscientific docking stations, the Custom Bus is always ineffective.
Wenyong Li, Ziwei Yu, Shuo Wei, Xiayun Lu, Yuanqing Zhang, Tao Wang   +5 more
doaj   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Optimal Resource Provision of Cloud Center with Guarantee Percentile Response Time

Dianxin kexue, 2015
In order to minimize resource provisioning cost of commercial cloud center，while guarantee percentile response time SLA，a cloud center model based on queuing theory was proposed.Resource provisioning cost was analyzed from an economic point of view，and ...
Huaiwen He
doaj   +2 more sources

Capacity Expansion and Reliability Evaluation on the Networks Flows with Continuous Stochastic Functional Capacity

Journal of Applied Mathematics, 2014
In many systems such as computer network, fuel distribution, and transportation system, it is necessary to change the capacity of some arcs in order to increase maximum flow value from source s to sink t, while the capacity change incurs minimum cost. In
F. Hamzezadeh, H. Salehi Fathabadi
doaj   +1 more source

Minimum Cost Flows in Graphs with Unit Capacities.

, 2015
We consider the minimum cost flow problem on graphs with unit capacities and its special cases. In previous studies, special purpose algorithms exploiting the fact that capacities are one have been developed. In contrast, for maximum flow with unit capacities, the best bounds are proven for slight modifications of classical blocking flow and push ...
Goldberg, Andrew V., Kaplan, Haim, Hed, Sagi, Tarjan, Robert E.   +3 more
openaire   +3 more sources