Results 51 to 60 of about 218,505 (300)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

ON NETWORK FLOW PROBLEMS WITH CONVEX COST

Journal of ICT, 2004
Minimum cost flow (MCF) problem is a typical example of network flow problems, for which an additional constraint of cost is added to each flow. Conventional MCF problems consider the cost constraints as linear functions of flow. In this paper, we extend
V. A. Nguyen, Y. P. Tan
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Multiple Objective Minimum Cost Flow Problems: A Review [PDF]

, 2005
In this paper, theory and algorithms for solving the multiple objective minimum cost flow problem are reviewed. For both the continuous and integer case exact and approximation algorithms are presented.
Hamacher, Horst W., Ruzika, Stefan, Pedersen, Christian   +2 more
core  

OPTIMIZACIÓN DE UNA RED DE TRANSPORTE COMBINADO PARA LA EXPORTACIÓN DEL CARBÓN DEL INTERIOR DE COLOMBIA OTIMIZAÇÃO DE UMA REDE DE TRANSPORTE COMBINADO PARA A EXPORTAÇÃO DO CARVÃO DO INTERIOR DA COLÔMBIA OPTIMIZATION OF A COMBINED EXPORT COAL TRANSPORT NETWORK FROM THE INTERIOR OF COLOMBIA

Revista EIA, 2011
Se estudia una red de transporte combinado en Colombia, con horizonte en el año 2019, con el propósito de identificar las rutas óptimas del carbón desde los distritos de producción localizados en el interior del país hasta los puertos marítimos de ...
Luis Gabriel Márquez
doaj  

A Gibbs Posterior Framework for Fair Clustering

Entropy
The rise of machine learning-driven decision-making has sparked a growing emphasis on algorithmic fairness. Within the realm of clustering, the notion of balance is utilized as a criterion for attaining fairness, which characterizes a clustering ...
Abhisek Chakraborty, Anirban Bhattacharya, Debdeep Pati   +2 more
doaj   +1 more source

The accumulation cost of relaxed fixed time accumulation mode

IET Intelligent Transport Systems, 2022
Studying the wagon accumulation process and the laws of accumulation cost is of great significance for determining the suitable conditions of wagon accumulation and shortening the accumulation time. Here, the process of relaxed fixed time accumulation is
Lianbo Deng, Enwei Jing, Jing Xu, Chen Chen   +3 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source