Results 101 to 110 of about 16,992,457 (248)

SVD-Based Image De-Nosing with the Minimum Energy Model

open access: yes, 2006
This paper proposes a new solution integrating energy function into singular value decomposition (SVD) for image de-noising. The singular values on the diagonal matrix obtained through SVD represent different components in image.
Shi ZL(史泽林)   +2 more
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Minimum Wages in a Symmetric Model of Monopsonistic Competition [PDF]

open access: yes
We reconsider the employment effect of a minimum wage on employment in a symmetric model of monopsonistic competition, where each employer competes equally with every other employer.
V. Bhaskar, Ted To
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Construction of ecological network of Southern Sichuan economic zone based on ecosystem services theory

open access: yes四川大学学报. 自然科学版
To improve the regional ecosystem service function and form a high-quality development land space grid, this study takes the Southern Sichuan economic zone as the research scope, uses the ecosystem service assessment results to extract the ecological ...
KANG Ao, ZHOU Xin-Ying, GAN Xiao-Yu
doaj  

Research on the Evaluation and Spatial Distribution Optimization of the Field Intensity Effect of Rural Basic Education Infrastructure in Wuhan’s New Urban District: A Case Study of Liji Township

open access: yesISPRS International Journal of Geo-Information
Education infrastructure is a critical public service facility in rural areas. The evaluation of rural education infrastructure could have important implications for the spatial distribution optimization of public educational services in countryside ...
Liang Jiang   +3 more
doaj   +1 more source

Cumulative Index: Index Digest [PDF]

open access: yes, 1943
Cumulative Index: Index ...
Montana Law Review, Index Digest, Cumulative
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

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