Results 41 to 50 of about 16,992,457 (248)
The evaluation of ecological risk and the construction of ecological security patterns are significant for the conservation of World Natural Heritage sites with high outstanding universal value.
Xiaodong Chen +3 more
doaj +1 more source
Preference modelling approaches based on cumulative functions using simulation with applications [PDF]
In decision making problems under uncertainty, Mean Variance Model (MVM) consistent with Expected Utility Theory (EUT) plays an important role in ranking preferences for various alternative options.
Fatah, Khwazbeen Saida
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Construction of Land Ecological Security Pattern in Main Agricultural Production Areas
In order to ensure the safety of the ecosystem in the main grain production area in northeast China,especially the security of the agricultural ecosystem,Kedong County,the main agricultural production area in Heilongjiang Province,was used as the ...
ZHANG Hui +4 more
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The development of transportation infrastructure disrupts wildlife movement, leading to habitat fragmentation and roadkill. While the establishment of wildlife corridors is a global strategy to mitigate these impacts, research on the intersections ...
Yangang Yang +4 more
doaj +1 more source
Statistical Modelling of Nonlinear Long-Term Cumulative Effects [PDF]
In epidemiology, bio-environmental research, and many other scientific areas, the possible long-term cumulative effect of certain factors has been well acknowledged, air pollution on public health, exposure to radiation as a possible cause of cancer ...
Kong, Efang, Tong, Howell, Xia, Yingcun
core
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source

