Results 91 to 100 of about 477,458 (300)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Maximum flows and minimum cuts in the plane [PDF]
Journal of Global Optimization, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Study on Dynamic Minimum Thickness of Cut by Nanoscratch Testing
, 2011 Nanoscratch tests showing clear ploughing behavior and stable chip formation was conducted to investigate the influence of friction coefficient on the minimum thickness of cut.
Hua Li Zhang, Fei Hu Zhang, Ji Cai Kuai
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Practical Performance of Efficient Minimum Cut Algorithms [PDF]
, 2000 In the late eighties and early nineties, three major exciting new developments (and some ramifications) in the computation of minimum capacity cuts occurred and these developments motivated us to evaluate the old and new methods experimentally.
Rinaldi, Giovanni +2 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A distributed minimum cut approximation scheme [PDF]
Proceedings of the 26th ACM symposium on Parallelism in algorithms and architectures, 2014 In this paper, we study the problem of approximating the minimum cut in a distributed message-passing model, the CONGEST model. The minimum cut problem has been well-studied in the context of centralized algorithms. However, there were no known non-trivial algorithms in the distributed model until the recent work of Ghaffari and Kuhn.
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Minimum Fundamental Cut Basis Problem [PDF]
, 2004 Any tree in an undirected graph defines a fundamental cut basis. The minimum fundamental cut basis problem is to find a tree minimizing the weight of the corresponding basis.
Schwahn, Anne
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Electronic Notes in Discrete Mathematics, 2011 Abstract We studied the minimum cut cover problem that consists in finding a minimum cardinality family of cuts C of a graph G such that each edge of G belongs to at least one cut C ∈ C . This problem is NP -hard and arises in fault testing and diagnosis, pattern recognition, and biological identification.
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