Results 111 to 120 of about 477,458 (300)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Impact of water content on minimum miscibility pressure during CO2 flooding in high water-cut reservoirs [PDF]

open access: yesE3S Web of Conferences
This study focused on the X block stratum oil, specifically addressing the application of CO2 displacement technology in enhancing oil recovery under high water content conditions.
Zhao Fajun   +6 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Value of F-wave studies on the electrodiagnosis of carpal tunnel syndrome

open access: yesNeuropsychiatric Disease and Treatment, 2015
Murat Alemdar Sakarya University Education and Research Hospital, Sakarya, Turkey Background: F waves are late electrophysiological responses to antidromic activation of motor neurons and are used to evaluate the conduction along the whole length of ...
Alemdar M
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

A simple minimum T-cut algorithm

open access: yesDiscrete Applied Mathematics, 2003
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Parallel algorithms for the minimum cut and the minimum length tree layout problems

open access: yes, 1997
The minimum cut and minimum length linear arrangement problems usually occur in solving wiring problems and have a lot in common with job sequencing questions. Both problems are NP-complete for general graphs and in P for trees.
Gibbons, Alan   +5 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Experimental Study of Minimum Cut Algorithms

open access: yes, 1997
Recently, several new algorithms have been developed for the minimum cut problem. These algorithms are very different from the earlier ones and from each other and substantially improve worst-case time bounds for the problem.
Chandra S. Chekuri   +5 more
core   +1 more source

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