Results 91 to 100 of about 641,465 (260)
Dynamic Evaluation of Transformation Ability for Emergency Scientific Research Achievements Based on an Improved Minimum Distance-Maximum Entropy Combination Weighting Method: A Case Study of COVID-19 Epidemic Data. [PDF]
Tan Q, Hui J.
europepmc +1 more source
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
Using of Parallel Coordinates in Finding Minimum Distance in Time-Space
Airspace domain may be represented by a time-space consisting of a three-dimensional Cartesian coordinate system and time as the fourth dimension. A coordinate system provides a scheme for locating points given its coordinates and vice versa.
Olga Blazekova, Maria Vojtekova
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Insights into the binding and covalent inhibition mechanism of PF-07321332 to SARS-CoV-2 Mpro. [PDF]
Ngo ST, Nguyen TH, Tung NT, Mai BK.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The authors study the corn crop residue management system for 16 provinces in northern Thailand encompassing 127 agricultural cooperatives (co-ops), 974 corn fields and 274 customers.
Phonin Sirilak, Likasiri Chulin
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source

