Results 51 to 60 of about 619,850 (264)

Resolution of the Wicksell's equation by Minimum Distance Estimation

open access: yesImage Analysis and Stereology, 2019
The estimation of the grain size in granular materials is usually performed by 2D observations. Unfolding the grain size distribution from apparent 2D sizes is commonly referred as the corpuscle problem.
Dorian Depriester, Régis Kubler
doaj   +1 more source

Minimum distance estimation of ARFIMA processes

open access: yesComputational Statistics & Data Analysis, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Zevallos, M., Palma M., Wilfredo
openaire   +4 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

The Maximum Distance Problem and Minimum Spanning Trees

open access: yesInternational Journal of Analysis and Applications, 2021
Given a compact E⊂Rn and s>0, the maximum distance problem seeks a compact and connected subset of Rn of smallest one dimensional Hausdorff measure whose s-neighborhood covers E.
Enrique G. Alvarado   +2 more
doaj  

Minimum Average Distance Triangulations [PDF]

open access: yes, 2012
We study the problem of finding a triangulation T of a planar point set S such as to minimize the expected distance between two points x and y chosen uniformly at random from S. By distance we mean the length of the shortest path between x and y along edges of T. The length of a path is the sum of the weights of its edges.
openaire   +2 more sources

Minimum Distance Estimators for Dynamic Games [PDF]

open access: yesSSRN Electronic Journal, 2012
Summary: We develop a minimum distance estimator for dynamic games of incomplete information. We take a two-step approach, following \textit{V. J. Hotz} and \textit{R. A. Miller} [Rev. Econ. Stud. 60, No. 3, 497--529 (1993; Zbl 0788.90007)], based on the pseudo-model that does not solve the dynamic equilibrium so as to circumvent the potential ...
openaire   +4 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Optimal quinary cyclic codes with minimum distance four

open access: yesTongxin xuebao, 2017
Cyclic codes are an extremely important subclass of linear codes.They are widely used in the communication systems and data storage systems because they have efficient encoding and decoding algorithm.Until now,how to construct the optimal ternary cyclic ...
Ye TIAN, Yu-qing ZHANG, Yu-pu HU
doaj   +2 more sources

Comprehensive Statistical Analysis of Skiers’ Trajectories: Turning Points, Minimum Distances, and the Fundamental Diagram

open access: yesSensors
In recent years, an increasing number of accidents at ski resorts have raised significant safety concerns. To address these issues, it is essential to understand skiing traffic and the underlying dynamics.
Buchuan Zhang, Andreas Schadschneider
doaj   +1 more source

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