Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Daya Antibakteri Ekstrak Garlic terhadap Kadar Hambat Minimum (KHM) dan Kadar Bunuh Minimum (KBM) Streptococcus mutans pada Media Agar [PDF]
, 2015 The increased prevalence in active caries in Indonesia is still high at 53.2%. The impacts of dental caries are a disruption in the activity function of oral cavity that affects nutritional status, performance and quality of life.
Siti, Hidayati +2 more
core
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Medical Laboratory Journal, 2016 Background and Objective: Due to the continuous increase of multidrug-resistant Acinetobacter baumannii strains around the world, decision making for an effective treatment of infections caused by this organism depends on the results of antimicrobial ...
Abdollah Ardebili +2 more
doaj
The antibacterial effects of wild and cultivated Allium hirtifolium Boiss on Pseudomonas aeruginosa and Enterococcus faecalis and antibiotic resistance patterns of the strains using disk diffusion [PDF]
, 2016 The widespread use of antibiotics has recently led to increased drug resistance in most bacteria. The studies on antimicrobial properties of plant species, especially endemic plants, can help to use nature-based drugs, with greater efficacy, to control ...
Aleebrahim-Dehkordy, Elahe. +3 more
core
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
Effect of the Minimum Inhibitory Concentration of Vancomycin on the Clinical Outcome of Enterococcus faecium Bacteremia. [PDF]
In Vivo, 2023 Hoshi T +11 more
europepmc +1 more source
Antibacterial effects of ethanolic extract of walnut leaves (Juglans regia) on propionibacterium acnes [PDF]
, 2010 Background and Objective: Acne is one of the medical problems and propionibacterium acnes is the pathogenic agent that has received a considerable attention. Different parts of Juglans regia have been shown to have antibacterial activity on many bacteria.
Rafieian-Kopaei, Mahmoud. +2 more
core
Is the Minimum Inhibitory Concentration of Vancomycin an Infallible Predictor of the Clinical Outcome ofStaphylococcus aureusBacteremia Treated with Vancomycin? [PDF]
, 2009 Federico Pea, Pierluigi Viale
openalex +1 more source