Results 191 to 200 of about 440,166 (303)

Antibiotic Susceptibility and Minimum Inhibitory Concentration for Stenotrophomonas maltophilia Ocular Infections. [PDF]

Antibiotics (Basel), 2022
Ho MM, Sun MH, Wu WC, Lai CC, Yeh LK, Hwang YS, Hsiao CH, Chen KJ.   +7 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Clinical application of Vitek-derived minimum inhibitory concentration values: Proof of concept study. [PDF]

S Afr J Infect Dis, 2023
Lowman W.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

The Peak Plasma Concentration (Cmax)/Minimum Inhibitory Concentration (MIC) of bedaquiline and levofloxacin with special attention to the sputum conversion in the treatment of multidrug-resistant tuberculosis in Indonesia. [PDF]

PLoS One
Mariana N, Gayatri A, Widyahening IS, Bela B, Soedarsono S, Maemunah I, Rosamarlina R, Setiawaty V, Myneedu VP, Nelwan EJ, Ascobat P.   +10 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Global genomic and antimicrobial resistance profiling of Neisseria gonorrhoeae: Insights from whole genome sequencing and minimum inhibitory concentration analysis. [PDF]

PLoS Negl Trop Dis
Ebrahimi E, Hadi Z, Farsioo S, Hasani B, Badmasti F, Beig M, Sholeh M.   +6 more
europepmc   +1 more source

Rapid Minimum Inhibitory Concentration (MIC) Analysis Using Lyophilized Reagent Beads in a Novel Multiphase, Single-Vessel Assay. [PDF]

Antibiotics (Basel), 2023
Khire TS, Gao W, Bales B, Hsieh K, Grossmann G, Park DJM, O'Keefe C, Brown-Countess A, Peterson S, Chen FE, Lenigk R, Trick A, Wang TH, Puleo C.   +13 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Minimum Inhibitory Concentration and Antibiotic Sensitivity Patterns in Pediatric Patients With Urinary Tract Infections. [PDF]

Cureus
Ranjan A, Lakra PS, Sahu SS, Ankita, Tirkey K, Bose V, Birua H.   +6 more
europepmc   +1 more source