Results 171 to 180 of about 12,527 (214)

Measuring Minimum Inhibitory Concentrations in Mycobacteria

2009
An agar dilution method for measuring minimum inhibitory concentrations (MICs) of Mycobacterium tuberculosis, based on the method of proportion, is described. Mycobacterium strains are grown on Middlebrook 7H10 (or 7H11) agar medium with twofold serially diluted drug concentrations in order to determine specific inhibitory values.
Frederick A, Sirgel, Ian J F, Wiid, Paul D, van Helden   +2 more
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Practical implications for the interpretation of minimum plasma concentration/inhibitory concentration ratios

The Lancet, 2001
For a drug to be clinically useful, plasma concentrations of the agent must achieve effective concentrations. Logically, therefore, optimum administration of drugs includes selection of doses that provide adequate exposure. This approach has been successfully used during drug development—eg, for antibacterials 1 —and has been applied to agents used in ...
J, Montaner, A, Hill, E, Acosta
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Determining Minimum Inhibitory Concentrations in Liquid Cultures or on Solid Medium

2021
Antimicrobial susceptibility testing is the mainstay of tuberculosis drug development programs. In this chapter, we describe methods for determination of the minimum inhibitory concentration of compounds against Mycobacterium tuberculosis growing in liquid media as a function of carbon source, detergent, and environmental stress imposed by acidic pH as
Qinglan, Wang, Helena I M, Boshoff
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minimum inhibitory concentration (MIC)

2009
lowest concentration of an antibacterial agent that inhibits visible growth of a specific microorganism; → see also antiseptic.
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Correlation of minimum inhibitory concentration and beta-lactamase activity

Infection, 1977
The beta-lactamase activity of 510 recently isolated Enterobacteriaceae was investigated with a quantitative photometric test. Beta-lactamase could be detected in 55 percent of the Enterobacteriaceae. At the same time minimal inhibition concentration (MIC) of beta-lactam antibiotics was determined.
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Broth dilution minimum inhibitory concentrations: rationale for use of selected antimicrobial concentrations

Journal of Clinical Microbiology, 1979
A microdilution susceptibility testing procedure utilizing selected, clinically relevant concentrations of a large number of antimicrobial agents is described. A qualitative code designed to facilitate interpretation of quantitative results is coupled with each antimicrobial concentration.
F G, Witebsky, J D, Maclowry, S S, French   +2 more
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Computerized Interpretation of Minimum Inhibitory Concentration Antimicrobic Susceptibility Testing

American Journal of Clinical Pathology, 1981
Quantitative antimicrobic susceptibility tests by determining the minimum inhibitory concentration (MIC) are becoming more and more prevalent in United States laboratories. Interpretation of MIC values is complex and should be considered as part of the laboratory service.
R K, Wertz, J E, Swartzberg
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Effect of protein on ramoplanin broth microdilution minimum inhibitory concentrations

Diagnostic Microbiology and Infectious Disease, 1993
Ramoplanin is a glycolipodepsipeptide antibiotic active against Gram-positive bacteria. We observed that microdilution minimum inhibitory concentrations (MICs) were higher than those obtained in glass tubes or by agar dilution. Initial studies showed that these differences disappeared when 30% bovine serum was added to the broth. Further studies showed
R, Scotti, J K, Dulworth, M T, Kenny, B P, Goldstein   +3 more
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Clinical relevance of Minimum Inhibitory Concentrations (MICs)

Aquaculture, 2001
This paper considers the practical approach taken to choosing the best antibiotic treatment for a bacterial disease. Comparisons are made between minimum inhibitory concentration (MIC) and Disc Diffusion methods of determining antibiotic sensitivity of pathogenic bacteria in practice.
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A review on influencing factors on the minimum inhibitory concentration of essential oils

Critical Reviews in Food Science and Nutrition, 2017
With growing interest in essential oils as natural preservatives in the food industry, the literature is expanding enormously. To understand the antimicrobial activity of essential oils, the antimicrobial mechanism of individual essential oil (EO) compounds, and their minimum inhibitory concentrations (MICs), are interesting starting points for ...
Elien, Van de Vel, Imca, Sampers, Katleen, Raes   +2 more
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