Results 171 to 180 of about 440,166 (303)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

A Comparison of the Minimum Inhibitory Concentration of Antibiotics in Staphylococcus Species Isolated From Orthopedic and Respiratory Medicine Infections. [PDF]

Cureus, 2023
Tomoyama A, Kobayashi N, Choe H, Ike H, Yukizawa Y, Higashihira S, Takagawa S, Kumagai K, Inaba Y.   +8 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Fate of the resistance profile of drinking water biofilm exposed to a sub-minimum inhibitory concentration of ciprofloxacin. [PDF]

NPJ Antimicrob Resist
Rilstone V, Filion Y, Champagne P.
europepmc   +1 more source

Evaluation of Minimum Inhibitory Concentration of Heavy Metals Contained in Packaging Material Digest on Prominent Gut Microbiota. [PDF]

Int J Food Sci, 2023
Mukhi S, Dhanashree B, Srikantiah RM, Manjrekar P, Harish S.   +4 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Efecto bacteriostático y/o bactericida del xilitol sobre cultivos de Listeria monocytogenes

Archivos Latinoamericanos de Nutrición
Listeria monocytogenes ha sido considerado como un patógeno emergente causante de enfermedades alimentarias. En la búsqueda de una vía alterna biocontroladora de su propagación, se propone al xilitol como posible agente bacteriostático y/o bactericida ...
Alba Rosa Morón de Salim, Luis Guillermo Ramírez Mérida   +1 more
doaj  

Prediction of minimum inhibitory concentration of antibacterial peptides using geometric graph networks and dynamic loss functions. [PDF]

Brief Bioinform
Bin Y, Li J, Cao R, Wei P, Zheng C.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

ANIA: an inception-attention network for predicting minimum inhibitory concentration of antimicrobial peptides. [PDF]

Brief Bioinform
Chiu YP, Yao L, Tang Y, Chung CR, Pang Y, Chiang YC, Lee TY.   +6 more
europepmc   +1 more source