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The Lancet, 2001
For a drug to be clinically useful, plasma concentrations of the agent must achieve effective concentrations. Logically, therefore, optimum administration of drugs includes selection of doses that provide adequate exposure. This approach has been successfully used during drug development—eg, for antibacterials 1 —and has been applied to agents used in ...
J, Montaner, A, Hill, E, Acosta
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For a drug to be clinically useful, plasma concentrations of the agent must achieve effective concentrations. Logically, therefore, optimum administration of drugs includes selection of doses that provide adequate exposure. This approach has been successfully used during drug development—eg, for antibacterials 1 —and has been applied to agents used in ...
J, Montaner, A, Hill, E, Acosta
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Measuring Minimum Inhibitory Concentrations in Mycobacteria
2009An agar dilution method for measuring minimum inhibitory concentrations (MICs) of Mycobacterium tuberculosis, based on the method of proportion, is described. Mycobacterium strains are grown on Middlebrook 7H10 (or 7H11) agar medium with twofold serially diluted drug concentrations in order to determine specific inhibitory values.
Frederick A, Sirgel +2 more
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Minimum Inhibitory Concentration Testing Services
2023Minimum Inhibitory Concentration Testing Services for the research community.
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Computerized Interpretation of Minimum Inhibitory Concentration Antimicrobic Susceptibility Testing
American Journal of Clinical Pathology, 1981Quantitative antimicrobic susceptibility tests by determining the minimum inhibitory concentration (MIC) are becoming more and more prevalent in United States laboratories. Interpretation of MIC values is complex and should be considered as part of the laboratory service.
R K, Wertz, J E, Swartzberg
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Journal of Antimicrobial Chemotherapy, 1985
Minimal bactericidal concentrations (MBCs) of nine antimicrobial agents were determined for clinical isolates by a replica plating method. Membranes were placed on the antibiotic-containing plates and the organisms replicated onto the membranes. After 18 h incubation the minimal inhibitory concentrations (MICs) were determined, the membranes were ...
Clarence J. Fernandes +4 more
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Minimal bactericidal concentrations (MBCs) of nine antimicrobial agents were determined for clinical isolates by a replica plating method. Membranes were placed on the antibiotic-containing plates and the organisms replicated onto the membranes. After 18 h incubation the minimal inhibitory concentrations (MICs) were determined, the membranes were ...
Clarence J. Fernandes +4 more
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Journal of Clinical Microbiology, 1979
A microdilution susceptibility testing procedure utilizing selected, clinically relevant concentrations of a large number of antimicrobial agents is described. A qualitative code designed to facilitate interpretation of quantitative results is coupled with each antimicrobial concentration.
F G, Witebsky +2 more
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A microdilution susceptibility testing procedure utilizing selected, clinically relevant concentrations of a large number of antimicrobial agents is described. A qualitative code designed to facilitate interpretation of quantitative results is coupled with each antimicrobial concentration.
F G, Witebsky +2 more
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Clinical relevance of Minimum Inhibitory Concentrations (MICs)
Aquaculture, 2001This paper considers the practical approach taken to choosing the best antibiotic treatment for a bacterial disease. Comparisons are made between minimum inhibitory concentration (MIC) and Disc Diffusion methods of determining antibiotic sensitivity of pathogenic bacteria in practice.
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minimum inhibitory concentration (MIC)
2009lowest concentration of an antibacterial agent that inhibits visible growth of a specific microorganism; → see also antiseptic.
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