Results 41 to 50 of about 7,275,625 (295)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Estimation in Gaussian Noise: Properties of the Minimum Mean-Square Error [PDF]

IEEE Transactions on Information Theory, 2011
Consider the minimum mean-square error (MMSE) of estimating an arbitrary random variable from its observation contaminated by Gaussian noise. The MMSE can be regarded as a function of the signal-to-noise ratio (SNR) as well as a functional of the input distribution (of the random variable to be estimated).
Dongning Guo, Yihong Wu 0001, Shlomo Shamai (Shitz), Sergio Verdú   +3 more
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Space-time decision feedback equalisation using a minimum bit error rate design for single-input multi-output channels

, 2007
This contribution proposes a minimum bit error rate (MBER) decision feedback equaliser (DFE) designed for single-input multiple-output (SIMO) systems employing a quadrature phase shift keying (QPSK) modulation scheme. It is shown that this MBER design is
Shi, Y., Wolfgang, A., Hanzo, L., Chen, S.   +3 more
core   +1 more source

Multicriteria Learning: Combining Minimum Mean Square Error, Minimum Error Entropy, and Maximum Correntropy in the Presence of Gaussian and Non-Gaussian Noises

IET Signal Processing
Understanding natural phenomena relies heavily on learning criteria aimed at minimizing model errors and enhancing fidelity to real-world conditions.
Fatemeh Mohamaddust, Saeid Pakravan, Ghosheh Abed Hodtani   +2 more
doaj   +1 more source

Machine Learning Techniques for Sugarcane Yield Prediction Using Weather Variables [PDF]

BIO Web of Conferences
Weather has a profound influence on crop growth, development and yield. The present study deals with the use of weather parameters for sugarcane yield forecasting.
Ramadhan Ali J., Priya S. R. Krishna, Pavithra V., Mishra Pradeep, Dash Abhiram, Abotaleb Mostafa, Alkattan Hussein, Albadran Zainalabideen   +7 more
doaj   +1 more source

Novel Modeling and Filtering for Stochastic Switched Systems With Heterogeneous Behaviors

IEEE Access, 2020
A novel heterogeneous behavior representation for linear stochastic switched system is proposed in the discrete-time domain. The switching modes of state evolution and measurement output are described by two random sequences with known probability ...
Wei Wang, Wenyong Yan, Jie Zhou
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Iterative Multiuser Minimum Symbol Error Rate Beamforming Aided QAM Receiver

, 2008
A novel iterative soft interference cancellation (SIC) aided beamforming receiver is developed for high-throughput quadrature amplitude modulation systems.
Tan, S., Chen, Sheng, Hanzo, L.
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source