Results 61 to 70 of about 6,870,463 (245)
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Proportionate Minimum Error Entropy Algorithm for Sparse System Identification
Entropy, 2015 Sparse system identification has received a great deal of attention due to its broad applicability. The proportionate normalized least mean square (PNLMS) algorithm, as a popular tool, achieves excellent performance for sparse system identification.
Zongze Wu +4 more
doaj +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Impact of signaling schemes on iterative linear minimum-mean-square-error detection
, 2008 In this paper, we study the iterative detection problem for a coded system with multi-ary modulation. We show that, with iterative linear minimum-mean-square-error (LMMSE) detection, superposition coded modulation (SCM) can provide performance superior ...
Jun Tong (19588204) +3 more
core +1 more source
Reduced-Rank Chip-Level MMSE Equalization for the 3G CDMA Forward Link with Code-Multiplexed Pilot
EURASIP Journal on Advances in Signal Processing, 2002 This paper deals with synchronous direct-sequence code-division multiple access (CDMA) transmission using orthogonal channel codes in frequency selective multipath, motivated by the forward link in 3G CDMA systems.
Goldstein J Scott +2 more
doaj +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Shadow detection with multi-feature fusion and MMSE optimization
Dianzi Jishu Yingyong, 2018 In order to reduce the interference of shadow to detection results of moving targets, a shadow detection method is proposed, which can be made as the post-processing step of motion detection methods.
Zhang Han, Yan Huaiping, Zhang Zhan
doaj +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Annals of Clinical and Translational Neurology, EarlyView.Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source