Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
An enhanced approach to minimum variance unbiased velocity estimation, incorporating horizontal and vertical handoff in HetNets. [PDF]
Sci RepTiwari R +5 more
europepmc +1 more source
Photoacoustic image formation based on sparse regularization of minimum variance beamformer. [PDF]
Biomed Opt Express, 2018 Paridar R +3 more
europepmc +1 more source
Hedging European Derivatives with the Polynomial Variance Swap under Uncertain Volatility Environments [PDF]
This paper proposes a new hedging scheme of European derivatives under uncertain volatility environments, in which a weighted variance swap called the polynomial variance swap is added to the Black-Scholes delta hedging for managing exposure to ...
Yukihiro Tsuzuki +2 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
A 33 GHz Conformal Phased-Array Radar with Linearly Constrained Minimum Variance Digital Beamforming, Circular- Polarization Filtering, and Neural-Network Micro-Doppler Classification for Counter-UAS Applications. [PDF]
Sensors (Basel)Baginski M.
europepmc +1 more source
Minimum variance rooting of phylogenetic trees and implications for species tree reconstruction. [PDF]
PLoS One, 2017 Mai U, Sayyari E, Mirarab S.
europepmc +1 more source
The effect of realised volatility on stock returns risk estimates [PDF]
In this paper, we estimate minimum capital risk requirements for short, long positions and three investment horizons, using the traditional GARCH model and two other GARCH-type models that incorporate the possibility of asymmetric responses of volatility
Aurea Grane, Helena Veiga
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Improving Ultrasound B-Mode Image Quality with Coherent Plane-Wave Compounding Using Adaptive Beamformers Based on Minimum Variance. [PDF]
Sensors (Basel)Neves LC +5 more
europepmc +1 more source