Results 31 to 40 of about 109,617 (265)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Adaptive Stochastic Optimization for Ultimate Pit Design in Disseminated Gold Deposits: A Validated Framework [PDF]
JES: Journal of Engineering SciencesThis study presents a novel adaptive stochastic framework for ultimate pit optimization in disseminated gold deposits, specifically addressing grade uncertainty that often leads to reserve write-downs in deterministic approaches.
Mohamed Abdelmawla +3 more
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Geofluids, 2022 During upward backfill mining of the close-distance coal seam group, the reasonable design of the backfill body compaction ratio (BBCR) of lower coal seam goaf plays a key role in controlling overburden strata movement and deformation. In this paper, the
Xingping Lai +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Digital Mining Technology-Based Teaching Mode for Mining Engineering
International Journal of Emerging Technologies in Learning (iJET), 2016 In this paper, the main problem in present mining engineering teaching was analyzed. Based on the analysis, the study of bringing digital mining technology into mining engineering teaching was presented. Furthermore, a new mining engineering teaching mode that includes mining knowledge demonstration, mining expertise building, mining environment ...
Zhongqiang Chen +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Scientific ReportsUnder the typical condition of deep buried weakly cemented overburden, the mining roadway is affected by strong mining stress and high ground stress, its stress environment is complicated, and the disaster behaviors are severe.
Shenglong Yang +5 more
doaj +1 more source
Energy Science & Engineering, 2022 Extra‐thick coal seams are widely distributed in the Datong mine area in China. The rapid stopping of mining and the support withdrawal technology for extra‐thick coal seams need to be developed urgently. The reasonable stopping top coal caving distance,
Shengrong Xie +9 more
doaj +1 more source
The Editorship of the Engineering and Mining Journal [PDF]
Science, 1905 n ...
openaire +3 more sources