Results 41 to 50 of about 4,015,604 (307)

The relationship between work-related psychological health and psychological type among clergy serving in the Presbyterian Church (USA) [PDF]

open access: yes, 2008
This study examines the relationship between work-related psychological health and the Jungian model of psychological type among a sample of 748 clergy serving within The Presbyterian Church (USA).
Francis, Leslie J.   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Figure of Distrust: Prince A.S. Menshikov in the Maritime Department during the Period of Reforms, 1826–1828

open access: yesHistoria provinciae: журнал региональной истории, 2020
The article considers the role of Prince A. Menshikov as a specific type of agent of supreme authority in the process of reforming the maritime administration.
Kseniya V. Donik
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Effect of Nizam al Mulk’s Siastat Nameh (Siaral- Moluk) on Seljuk Rule [PDF]

open access: yesپژوهش‌های تاریخی ایران و اسلام, 2013
Mlkshah Seljuk commissioned a group of scholars making up to write a book on statecraft He aims to strengthen the state's administrative and political behavior of the people who write policies and compilation of Nizam al-Mulk was highlighted and choose ...
عباس سرافرازی
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Church in the Christian Bible

open access: yesSt Andrews Encyclopaedia of Theology, 2023
The theme of ‘church’ in the New Testament raises four central questions, the answers to which are essential for Christian theology. The questions are there for all, because of the text; but the answers are of different importance, due to the different ...
Thomas Söding
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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