Results 71 to 80 of about 3,982,795 (307)
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Ministry and Ministries in the Church
This article examines the long-standing issue of ministry and the ministries in the Church. The hermeneutical principle providing the foundation for this contribution is the correspondence between model of the Church and model of ministry. Where they do not correspond to oneanother, both suffer.
Vitali, Dario, Vitali, Dario
openaire +3 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Dziekan a duchowieństwo dekanalne. Aspekt prawno-duszpasterski
The aim of the article is to discuss the issue of the legal relations between the vicar forane and the clerics of the vicariate forane. The first part deals with the vicar forane’s care for the suitable spiritual life of the clerics.
Jerzy Adamczyk
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Contextualization: Tanzanian Maasai Culture and the Implications for Worship and Women’s Ministry [PDF]
Maasai religion, music, and cultural customs have a definite impact on the methodology of missions and relations with the people of their tribes, specifically in the areas of worship and women’s ministry.
Morgan, Alexandra T
core +1 more source
Justice and Gender in Ministry: Debating Women\u27s Ordination [PDF]
Much has been written on the question of ordaining women in the Roman Catholic Church. Catholic scholars of all stripes have debated issues such as the biblical sources for a theology of ordination; the relationship between sacramental and non ...
Ryan, Maura A.
core +2 more sources
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source

