Results 31 to 40 of about 926,976 (243)

Assessment of Quality of Life in a Sample of Iraqi Patients with Psoriasis.

Iraqi Journal of Pharmaceutical Sciences, 2020
Psoriasis is a dermatological, chronic, immune-mediated condition. Psoriasis symptoms are not associated with physical burden only, but it may also have psychosocial effects on patients, diminished cognitive control, poor body image and impairments in ...
Sarah H. Abdulridha, Dheyaa J. Kadhim, Sarmad A. Abdul Razzak   +2 more
doaj   +1 more source

Role of vaccine science diplomacy in low-middle-income countries for eradicating the vaccine-preventable diseases: Targeting the “LAST MILE”

Journal of Family Medicine and Primary Care, 2021
The meaning of “vaccine diplomacy (VD)” is defined as “the use of vaccines to increase a country's diplomatic relations and influence over other nations.” The golden era of vaccine science diplomacy started during the time of Cold War between the United ...
Sudip Bhattacharya, Sheikh Mohd Saleem, Deep Shikha, Ozden Gokdemir, Kedar Mehta   +4 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Optimization and development of ondansetron HCl nanocrystals by using D-optimal design expert® and in-vitro characterization

Pakistan Journal of Pharmaceutical Sciences
Background: Over the last few years, nanocrystal technology has expanded to improve the bioavailability of poorly water-soluble drugs, which is challenging.
Zainab A. Almusawi, Eman B.H. Alkhedairy Thiqar Health Directorate, Ministry of Health, Environment, Thiqar, Iraq   +5 more
doaj   +1 more source

Evaluation of the Effect of Topical Artemisia dracunculus Administration on Serum Levels of Selected Interleukins and Spleen Index in Imiquimod-Induced Psoriasis in Male Mice Compared to Clobetasol Propionate (Dermovate (R)) Ointment

Iraqi Journal of Pharmaceutical Sciences, 2020
Psoriasis is a long-lasting autoimmune disease that is characterized by swollen skin patches. Normally, these skin patches are dark, swollen, itchy and scaly.
Thamer M. Mohammed, Shihab H. Mutlag, Bahaa A.Shihab   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Opinions of syrian refugee and turkish citizen pregnant women regarding the ministry of health's practices to combating smoking

Medicine Science, 2022
Laws have been enacted by the Ministry of Health to protect health against smoking. We aimed to contribute to the literature by examining the opinions of the citizens of the Republic of Turkey, which was presented as a role model by the World Health ...
Remziye Can, Serif Kurtulus
doaj   +1 more source