Results 41 to 50 of about 583,399 (306)

Fort Snelling as I Knew It

Open Rivers, 2017
When he was nine, my brother Steven enlisted the rest of the kids in our isolated neighborhood to help him build earthworks in the empty field behind our house. Not a fort—we already lived in one of those—but a replica of Little Round Top, a crucial site
Catherine Watson
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

The Story Behind a Nassau Bottle Excavated at Historic Fort Snelling

Open Rivers, 2018
For millennia, Native American people traveled and traded on the Mississippi River. When colonial powers moved into North America, they quickly saw the importance of controlling transportation and the movement of goods on the river.
Nancy Buck Hoffman
doaj   +1 more source

Personality Disorders in Patients with Human Immunodeficiency Virus [PDF]

Journal of Social Behavior and Community Health, 2023
No ...
Abbas Boosazar, Elnaz Shahmohamadi, Seyeh Ahmad SeyedAlinaghi   +2 more
doaj  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

On The Uncompromising Hand: Remembering Spirit Island

Open Rivers, 2018
Drawing as Imagining Absence: Sometime prior to 1963 a person sat down at a table to draw a map. This person could effectively communicate with lines across a page, possessing the technical skills of rendering exact scale ratios of a three-dimensional ...
Andrea Carlson
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Mosquitoes, Muck, and Mussels: A Look Into Scientific Research

Open Rivers, 2018
The aspiring young undergraduate scientists envision fieldwork as a romantic escape from the office cubicle, classroom desk, and seemingly endless pile of homework.
Lea Davidson, James Doherty, Laura Gould, and Hayley Stutzman
doaj   +1 more source

Minnesota Nutrition Conference 75. Front Matter

, 2014
University of Minnesota. (2014). Minnesota Nutrition Conference 75. Front Matter.
University of Minnesota
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