Results 61 to 70 of about 1,558,347 (389)
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
When he was nine, my brother Steven enlisted the rest of the kids in our isolated neighborhood to help him build earthworks in the empty field behind our house. Not a fort—we already lived in one of those—but a replica of Little Round Top, a crucial site
Catherine Watson
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The Story Behind a Nassau Bottle Excavated at Historic Fort Snelling
For millennia, Native American people traveled and traded on the Mississippi River. When colonial powers moved into North America, they quickly saw the importance of controlling transportation and the movement of goods on the river.
Nancy Buck Hoffman
doaj +1 more source
Personality Disorders in Patients with Human Immunodeficiency Virus [PDF]
No ...
Abbas Boosazar +2 more
doaj
To assess the outlook for grantmaking in Minnesota in 2010, the Minnesota Council on Foundations (MCF) conducted its 2010 Outlook Report survey in October and November of 2009.
Anne Graham, Juliana Tillema, Wendy Wehr
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
On The Uncompromising Hand: Remembering Spirit Island
Drawing as Imagining Absence: Sometime prior to 1963 a person sat down at a table to draw a map. This person could effectively communicate with lines across a page, possessing the technical skills of rendering exact scale ratios of a three-dimensional ...
Andrea Carlson
doaj +1 more source
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source

