Results 71 to 80 of about 1,710,065 (268)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fatal neurocryptococcosis in a Colombian underage patient
Cryptococcosis is a life-threatening mycosis reported mainly in human adults with low frequency in children. High mortality rates may occur in cases with late diagnosis therefore, a timely suspicion of this pathology is important. Cryptococcus gattii is
Maria Clara Noguera +4 more
doaj +1 more source
Subscapularis minor – an analogue of the Teres minor?
The purpose of this study was to determine the role of the subscapularis (SSC) in forward flexion. We hypothesized that the inferior part of the SSC has a main role in the ability to preserve forward flexion in cases of anterosuperior rotator cuff tears.Active forward flexion of the shoulder was prospectively evaluated in patients presenting with Grade
Collin, Philippe +3 more
openaire +3 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Developing world: The minority minority [PDF]
Women are under-represented in physical sciences and in science in the developing world. Meet three who beat both sets of odds.
openaire +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Secret Memory. How the Goncourt 2021, Mohamed Mbougar Sarr, Rewrites the Story of the “Black Rimbaud”. In a mixture of “savage detective story” à la Bolaño, of diary, journalism, interviews and discussions on “plagiarism,” the revolutionary book of ...
Laura T. ILEA
doaj +1 more source

