Results 61 to 70 of about 7,464 (129)

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, Volume 13, Issue 44, 7 August 2026.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

Advanced Science, Volume 13, Issue 44, 7 August 2026.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng, Chao He, Zhibin He, Hongbo Chen, Fang Cheng, Yongjiang Zheng   +5 more
wiley   +1 more source

Innate Immune Cells in Non‐Small Cell Lung Cancer: Roles in Tumor Progression and Therapeutic Responses

Cancer Innovation, Volume 5, Issue 4, August 2026.
Innate immune cells (IICs) are not only as first‐line defenders or simple auxiliaries to adaptive immunity, but also as decisive regulators of non‐small cell lung cancer progression and treatment outcomes. ABSTRACT As a leading cause of cancer‐related morbidity and mortality worldwide, non‐small cell lung cancer (NSCLC) is profoundly influenced by ...
Jiaxin Liu, Jie Jia, Chong Wang, Zongru Zhou, Zhuoyu Cheng, Ziyi Zhang, Xueyi Jiang, Ziyu Huang, Chunyan Li   +8 more
wiley   +1 more source

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun, Linqing Wen, Shiyun Tang, Lu Liu, Nianzhi Chen   +4 more
wiley   +1 more source

Engineered Bacterial Membranes as Next‐Generation Platforms for Cancer Immunotherapy

Small Science, Volume 6, Issue 8, August 2026.
Engineered bacterial membrane platforms, including outer membrane vesicles, bacterial ghosts, genetically engineered membranes, and hybrid bacterial–tumor membranes, integrate tumor antigen presentation with intrinsic immune stimulation. These platforms promote dendritic‐cell activation, T‐cell priming, pyroptosis, and synergistic responses with ...
Hafiza Aasia Malik, Urooj Yousaf Virk, Mohamed Salah Attia, Jenny Wilson, Ming Wei   +4 more
wiley   +1 more source

Dendritic cell‐specific hypoxia‐inducible factor‐1α deficiency protects mice from recurrent retroviral infection

Experimental Physiology, Volume 111, Issue 8, Page 3843-3856, 1 August 2026.
Abstract Antigen‐processing and ‐presenting cells play a pivotal role in initiation of the antiviral immune response. The cellular adaption of dendritic cells to reduced oxygen and nutrition levels at the site of infection is regulated predominantly by the transcription factor complex hypoxia‐inducible factor‐1 (HIF‐1).
Timm Schreiber, Yvonne Hüsecken, Claudia Lodewick, Simone Schimmer, Gennadiy Zelinskyy, Ulf Dittmer, Kathrin Sutter, Joachim Fandrey, Sandra Winning   +8 more
wiley   +1 more source

The potential of a novel Adenovirus vector for vaccination [PDF]

Adenoviruses (Ads) have many attractive characteristics for use as agents of genebased vaccines and therapies. The most frequently used Ad vectors in preclinical research are based on Ad5.
Martin, Stuart
core  

The Class I Scavenger Receptors CD5 and CD6 Play a Role in the Early Peritoneal Immune Response to <i>Echinococcus granulosus</i> Tegumental Antigens. [PDF]

Int J Mol Sci
García-Luna J, Català C, Dematteis S, Lozano F, Velasco-De-Andrés M, Mourglia-Ettlin G.   +5 more
europepmc   +1 more source

Extracorporeal photopheresis reduces the T cell stimulatory capacity of human primary blood conventional dendritic cells type 1. [PDF]

Front Immunol
Heger L, Berking C, Hackstein H.
europepmc   +1 more source

Induced pluripotent stem cell-derived dendritic cells potentiate the efficacy of interleukin-12-expressing oncolytic HSV-1. [PDF]

Mol Ther Oncol
Taguchi S, Fukuhara H, Cai S, Li XK, Naito A, Kakutani S, Takeshima Y, Miyakawa J, Kume H, Todo T.   +9 more
europepmc   +1 more source