Results 61 to 70 of about 722,667 (218)

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Serum Lipids in Turkish Patients with β-Thalassemia Major and β-Thalassemia Minor

Turkish Journal of Hematology, 2016
Abstract Not ...
Işık Balcı Y, Ünal Ş, Gümrük F
openaire   +6 more sources

Prevalence of B-Thalassemia Carriers Among a Cohort of University Students in Hawler Province of Iraqi Kurdistan

Iraqi Journal of Pharmaceutical Sciences, 2017
A representative sample of a thousand volunteer university students was screened for evidence of thalassemia minor.Complete blood counts using automated blood cell analysers and blood smears were examined.
Abdulkadir A. Alnakshabandi, Huda A. Muhammad   +1 more
doaj   +1 more source

Non‐Invasive Prenatal Diagnosis of Haemoglobinopathies: From Concept to Clinical Reality

Prenatal Diagnosis, EarlyView.
ABSTRACT Haemoglobinopathies are the most prevalent monogenic disorders worldwide, contributing significantly to childhood morbidity and mortality. Preventive strategies, including carrier screening and prenatal diagnosis, have successfully reduced disease incidence in regions with established programmes.
Irene Leonidou, Leila Sallie, Morgan Jean Bell‐Ricketts, Alexandros Abdel Massih, Lisa Joy Kaiser, Ashley Hoi Kiu Wong, María Teresa Martín Monreal, Panicos Shangaris   +7 more
wiley   +1 more source

Carrying a crisis: The risk of a painful sickle cell crisis during pregnancy

British Journal of Haematology, EarlyView.
Commentary on: Auger et al. Sickle cell anaemia with and without crises: An observational study of pregnancy outcomes. Br J Haematol 2026 (Online ahead of print). doi: 10.1111/bjh.70837.
Bart J. Biemond
wiley   +1 more source

Blood Indices of the Patients with β-Thalassemia Minor Compared to the Patients with β-Thalassemia Minor-Alpha-Thalassemia

Immunology and Genetics Journal
Objective: Thalassemia, as one of the most common genetic diseases, is a group of hereditary hemoglobin disorders due to a slight disturbance in the production of alpha and beta globin chains in the structure of hemoglobin occurs. There are still no clear criteria for differentiating thalassemia types based on hematological findings.
Bijan Keikhaei Dehdezi, Najmeh Namehgoshay Fard   +1 more
openaire   +1 more source

Sickle cell anaemia with and without crises: An observational study of pregnancy outcomes

British Journal of Haematology, EarlyView.
Summary We assessed the pregnancy outcomes of patients with sickle cell crises. We carried out a retrospective study of 2 698 556 pregnancies in Quebec, Canada between 1989 and 2022. The primary exposure was sickle cell anaemia with crisis during or outside of pregnancy. Outcomes included severe maternal morbidity and other pregnancy complications.
Nathalie Auger, Émilia Mailhot‐Diaferia, Gabriel Côté‐Corriveau, Gilles Paradis, Antoine Lewin, Aimina Ayoub, Anne‐Marie Parrot, Ashley Park, Brian Potter   +8 more
wiley   +1 more source

A very unusual case report: Retinal neovascularization and tractional retinal detachment in a patient with thalassemia minor

Taiwan Journal of Ophthalmology
Although many ocular pathologies have been reported in patients with thalassemia major, there is a limited number of studies on the ocular findings of patients with thalassemia minor.
Durgul Acan, Eyyup Karahan
doaj   +1 more source

Off‐Label use of a lumen‐apposing metal stent for refractory pyloric stricture in a toddler

JPGN Reports, EarlyView.
Hamza Hassan Khan, Prateek Wali, Sumant Inamdar   +2 more
wiley   +1 more source

Phase 3, randomised, placebo‐controlled trial of voxelotor for the resolution of leg ulcers in sickle cell disease: RESOLVE

British Journal of Haematology, EarlyView.
In this trial, conducted in Kenya, Nigeria and Brazil, the resolution of leg ulcers was similar between the voxelotor and placebo arms. In the 12‐week blinded period, the number of sickle cell anaemia with crisis events was higher in the voxelotor arm compared to placebo.
Bernhards Ogutu, Janet Oyieko, Halima Bello‐Manga, Adeseye Akinsete, Jessie Githanga, José Valber Lima Meneses, Carolyn Hoppe, Mark W. Davis, Jeremy Rupon, Ching‐Ray Yu, Roberto Pinto, Elena Tudone, Ibrahim Musa Idris, Martin Meremikwu, Aderson da Silva Araújo, Rodolfo D. Cançado, Guilherme Fonseca, Patrícia Santos Resende Cardoso, Obiageli Eunice Nnodu, on behalf of the RESOLVE Investigators   +19 more
wiley   +1 more source