Results 21 to 30 of about 12,026,382 (209)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Overview of Minority Health and Health Disparities in the US [PDF]
, 2006 Understanding health disparities involves a critical analysis of historical, political, economic, social, cultural, and environmental conditions that have produced an inequitable health status for racial and ethnic minorities in the United States.
Thomas, Stephen B, Gilbert, Keon L
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
BMC Public HealthBackground The COVID-19 pandemic had a profound social and economic impact across the United States due to the lockdowns and consequent changes to everyday activities in social spaces.
Stephanie A Ponce +3 more
doaj +1 more source
Frontiers in Public Health, 2021 Introduction: Long–standing disparities in colorectal cancer (CRC) outcomes and survival between Whites and Blacks have been observed. A person–centered approach using latent class analysis (LCA) is a novel methodology to assess and address CRC health ...
Francisco A. Montiel Ishino +6 more
doaj +1 more source
Maryland Plan to Eliminate Minority Health Disparities Plan of Action 2010 – 2014 [PDF]
, 2010 The Department of Health and Mental Hygiene is pleased to present the Maryland Plan to Eliminate Minority Health Disparities, Plan of Action 2010-2014. This document, published by the Maryland Office of Minority Health and Health Disparities (MHHD), is ...
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FDA’s Strategies to Close the Health Equity Gap among Diverse Populations
Journal of Primary Care & Community Health, 2021 This commentary provides an overview of the Food and Drug Administration’s Office of Minority Health and Health Equity.
Jovonni Spinner, RADM Richardae Araojo
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
BMJ Open, 2023 Introduction The COVID-19 pandemic has had drastic effects on worldwide mental health and laid bare health disparities and inequities among marginalised groups and racial/ethnic minoritised communities in the USA.
Faustine Williams +4 more
doaj +1 more source