Results 41 to 50 of about 12,026,382 (209)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Evaluating the implementation of Nuevo Amanecer-II in rural community settings using mixed methods and equity frameworks

open access: yesArchives of Public Health, 2023
Background The 10-week Nuevo Amanecer-II intervention, tested through a randomized controlled trial, reduced anxiety and improved stress management skills among Spanish-speaking Latina breast cancer survivors.
Jasmine Santoyo-Olsson   +10 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Incorporating community-engaged research into a statewide community health worker-driven infrastructure for addressing health disparities in public health emergency

open access: yesBMC Health Services Research
Background Emergency response plans in unprecedented public health events prioritize community-based interventions for addressing health disparities. Due to their close connections and shared values with community members, positioning community health ...
Azeez B. Aina   +23 more
doaj   +1 more source

Exploring changes in cigar smoking patterns and motivations to quit cigars among black young adults in the time of COVID-19

open access: yesAddictive Behaviors Reports, 2020
Introduction: The COVID-19 pandemic has disproportionately impacted the Black/African American communities in the U.S. The objective of this study is to understand the change in cigar smoking patterns and motivations to quit cigars during the COVID-19 ...
Julia C. Chen-Sankey   +8 more
doaj   +1 more source

$4.8 Million Awarded to Pitt’s Center for Minority Health to Fund Health Disparities Research [PDF]

open access: yes, 2007
PITTSBURGH, November 8, 2007 The Center for Minority Health (CMH) in the Graduate School of Public Health (GSPH) at the University of Pittsburgh has been awarded a five-year, $4.8 million grant to establish a Research Center of Excellence in Minority ...

core  

Maryland Plan to Eliminate Minority Health Disparities: A Healthier Future for All Marylanders 2006-2010

open access: yes, 2006
The Department of Health and Mental Hygiene is pleased to present this first Maryland Plan to Eliminate Minority Health Disparities. Maryland is the sixth most diverse state in the nation and is approaching an ethnic majority.
Bhavsar, Sneha M.   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Clinical and sociodemographic characteristics associated with health-related quality of life among older breast cancer survivors

open access: yesWomen's Health
Background: Health-related quality of life (HRQoL) measures may help incorporate patient preferences and deliver individualized care for older breast cancer survivors.
Jacob Schneider   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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