Results 61 to 70 of about 1,366,927 (306)

Delivering effective NHS services to our multiethnic population: collection and application of ethnic monitoring within primary care [PDF]

, 2009
Government health policy has emphasised the importance of understanding and tackling ethnic disparities in health and healthcare for at least four decades. Yorkshire & the Humber includes areas with large, well-established minority ethnic populations.
Allmark, Peter, Salway, Sarah
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Incorporating community-engaged research into a statewide community health worker-driven infrastructure for addressing health disparities in public health emergency

BMC Health Services Research
Background Emergency response plans in unprecedented public health events prioritize community-based interventions for addressing health disparities. Due to their close connections and shared values with community members, positioning community health ...
Azeez B. Aina, Antoniette Holt, Ashley H. Meredith, Carey Frazier, Carla Harrison, Celeste Fonseca-Tames, Fransesca Lynnet, Jasmine D. Gonzalvo, Karina Buenavides, Kourtney A.D. Byrd, Lance Boozer, Latrice Ligon, Maeve Companik, Margarita Hart, Megan Conklin, Natalia M. Rodriguez, Olivia Zarate, Olunda Hunt, Rebecca Ziolkowski, Samantha Daniels, Charleston Sanders, Shamika Crowder, Yumary Ruiz, Omolola A. Adeoye-Olatunde   +23 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Relying on Visiting Foreign Doctors for Fistula Repair: The Profile of Women Attending Fistula Repair Surgery in Somalia

Obstetrics and Gynecology International, 2017
Obstetric fistula is treatable by surgery, although access is usually limited, particularly in the context of conflict. This study examines the profile of women attending fistula repair surgery in three hospitals in Somalia.
Abdi A. Gele, Abdulwahab M. Salad, Liban H. Jimale, Prabhjot Kour, Berit Austveg, Bernadette Kumar   +5 more
doaj   +1 more source

An observational study of immigrant mortality differences in Norway by reason for migration, length of stay and characteristics of sending countries

BMC Public Health, 2018
Background Knowledge of mortality differentials in immigrant groups depending on their reason for migration, length of stay in host countries and characteristics of sending countries may be beneficial for policy interventions aimed to improve various ...
Astri Syse, Minja T. Dzamarija, Bernadette N. Kumar, Esperanza Diaz   +3 more
doaj   +1 more source

Addressing Health Disparities Through Organizational Change - Evaluation Report [PDF]

, 2012
In the coming decades, racial and ethnic minorities will constitute more than 50% of many states' populations -- including that of Colorado. Individuals of racial and ethnic minority status are disproportionally affected by disease and disability and ...
Kien Lee, LaKeesha Woods
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

The Health Disparities Myth [PDF]

, 2006
Many experts today insist that bias in the doctor's office will lead to poorer treatment of minority patients. A new monograph by Jonathan Klick of Florida State University and AEI's Sally Satel, The Health Disparities Myth: Diagnosing the Treatment Gap (
Jonathan Klick, Sally Satel
core  

Using Formative Research and Audience-Centric Intelligence to Develop the #JustBe Digital Magazine: An mHealth Strategy to Improve Adolescent Sexual Health [PDF]

, 2017
Digital strategies may help to overcome challenges in providing contraception education to overlooked and key sub-populations (older teens, ethnic minority youth, LGBTQ youth, high school dropouts and males).
Cruz, Jorge, Cruz, Maribel, Edwards, Sharon, Johnson-Baker, Kimberly, Swain-Ogbonna, Honora I, Tortolero, Susan R.   +5 more
core   +2 more sources