Results 41 to 50 of about 13,776 (222)

Minoxidil in trichological practice

Медицинский совет, 2018
Management of patients with alopecia is still a challenging task. Minoxidil is a pyrimidine derivative, a potent KATP channel opener, and has been shown to act as a vasodilating agent.
O. Yu. Olisova, I. P. Gostroverkhova
doaj   +1 more source

Compounded Hair Solutions and Foams Containing Minoxidil: Does the Color Change Impact Stability?

Scientia Pharmaceutica, 2023
An increasing number of pharmacies around the world are producing hair solutions and foams containing minoxidil for alopecia, commonly using ready-to-use vehicles such as TrichoSolTM or TrichoFoamTM. However, it is paramount to determine the chemical and
Hudson C. Polonini, Carolina C. V. Silva
doaj   +1 more source

Comparative efficacy of minoxidil alone versus minoxidil combined with low-level laser therapy in the treatment of androgenic alopecia: a systematic review and meta-analysis

Journal of Dermatological Treatment
Objective This systematic review evaluates the efficacy of minoxidil alone versus minoxidil with low-level laser therapy (LLLT) for androgenic alopecia.Study design systematic review and meta-analysis.Methods An online search of PubMed, Web of Science ...
Abdulmajeed Alosaimi, Abdullah Algarni, Abdulrahman Alharbi, Abdulmalik Alotaibi, Abdullah Alomairi, Mohannad Alsurayhi, Waleed Alharbi   +6 more
doaj   +1 more source

Contact Dermatitis Caused by Topical Minoxidil: Allergy or Just Irritation

Acta Dermato-Venereologica
Topical minoxidil is the mainstay of treatment for androgenic alopecia and is also used off-label for other forms of hair loss. Despite its efficacy and favourable safety profile, the use of minoxidil is associated with various side effects, the most ...
Alexandra Junge, Susanne Radonjic-Hoesli, Simon Bossart, Dagmar Simon, Pierre de Viragh, Robert E. Hunger, Kristine Heidemeyer, S. Morteza Seyed Jafari   +7 more
doaj   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Application of topical minoxidil in acne vulgaris treatment

Dermatologica Sinica
Background: Acne vulgaris (AV) results from increased sebum production and Cutibacterium acnes (C. acnes) overgrowth, leading to pilosebaceous unit inflammation.
Chun-Bing Chen, Yung-Chia Kuo, Sun-Min Chang, An-Chi Lin, Hsien-Chi Fan, Tung-Liang Lin, Wen-Hung Chung, Cheng-Lung Hsu   +7 more
doaj   +1 more source

Glibenclamide inhibits cell growth by inducing G0/G1 arrest in the human breast cancer cell line MDA-MB-231 [PDF]

, 2013
Background: Glibenclamide (Gli) binds to the sulphonylurea receptor (SUR) that is a regulatory subunit of ATP-sensitive potassium channels (KATP channels).
Bergoc, Rosa Maria, Cocca, Claudia Marcela, Cricco, Graciela Patricia, Croci, Máximo, Martin, Gabriela Adriana, Medina, Vanina Araceli, Nuñez, Mariel Alejandra, Rivera, Elena   +7 more
core   +2 more sources

Arginine Metabolic Disruption Impairs Hair Regeneration via ROS‐Mediated Inactivation of mTOR Signaling in Androgenetic Alopecia

Advanced Science, EarlyView.
Arginine deficiency accelerates androgenetic alopecia. Serum metabolome shows reduced circulating arginine, while local metabolic disruption depletes follicular reserves, triggering reactive oxygen species (ROS) accumulation and mTOR suppression that induce hair miniaturization.
Shixin Duan, Guo Li, Yanji Chu, Junbo Zhang, Li Yang, Yujin Zhang, Fangfen Liu, Jiayun Li, Mengting Chen, Ben Wang, Zhixiang Zhao, Wei Shi, Yiya Zhang, Guangtong Deng, Xinwei Kuang, Hongfu Xie, Yufan Cheng, Zhili Deng, Ji Li, Yan Tang   +19 more
wiley   +1 more source

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source

Case Report of a Patient With Psoriasis Vulgaris, Psoriatic Arthritis and Alopecia Universalis Successfully Treated With Tofacitinib and Methotrexate

JEADV Clinical Practice, EarlyView.
Capsule Summary We present a case of a 31‐year‐old female with alopecia universalis, psoriasis vulgaris, and psoriatic arthritis, who showed poor response to prior treatments. Following the initiation of a combination therapy with tofacitinib and methotrexate, significant improvements in joint pain and hair regrowth were observed. This case underscores
Jan Nicolai Wagner, Matthias Augustin, Caroline Gewiss, Carolin Grote, Nesrine Ben‐Anaya   +4 more
wiley   +1 more source