Results 71 to 80 of about 168,210 (266)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Journal of Law, Politic and HumanitiesAn auction is a public sale of goods through bidding, requiring the issuance of an auction minutes (auction minutes). These minutes, prepared by an authorized auction official, are authentic deeds with perfect evidentiary strength. The study focuses on the notary's authority to draft auction minutes and their legal validity as authentic evidence in ...
null Agung Laksono +2 more
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Characterising exo-ringsystems around fast-rotating stars using the Rossiter-McLaughlin effect [PDF]
, 2017 Planetary rings produce a distinct shape distortion in transit lightcurves. However, to accurately model such lightcurves the observations need to cover the entire transit, especially ingress and egress, as well as an out-of-transit baseline.
de Mooij, E. J. W. +2 more
core +3 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Authentica, 2020 Cyber Notary is the use or utilization of information technology such as computers, computer networks, and/or other electronic media, such as teleconferences or video conferences in carrying out the tasks of the authority of a Notary Public. This study analyzes the authentication of electronic documents in the form of the minutes of the General Meeting
openaire +1 more source
Pertanggungjawaban Hukum Notaris terhadap Pengingkaran Akta Jual Beli Tanah Bersertipikat oleh Pihak yang Dirugikan [PDF]
, 2019 Pasal 1 Undang-Undang Nomor 2 Tahun 2014 tentang Jabatan Notaris: “Notaris merupakan Pejabat Umum yang berwenang membuat akta otentik.” Peraturan Pemerintah Nomor 24 Tahun 2016 Tentang Peraturan Jabatan Pejabat Pembuat Akta Tanah (PPAT), PPAT berwenang ...
Ali, D. (Dahlan) +2 more
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