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Comparative in vitro exoenzyme-suppressing activities of azithromycin and other macrolide antibiotics against Pseudomonas aeruginosa. [PDF]
Mizukane R +8 more
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Radioimmunoassay for metabolites of 9,3"-diacetylmidecamycin, a macrolide antibiotic. [PDF]
Shimada N +4 more
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Effect of miocamycin on theophylline kinetics in children
European Journal of Clinical Pharmacology, 1987The interaction between a new macrolide antibiotic, miocamycin, and theophylline was evaluated in a single cross-over study in 5 asthmatic children. Each patient received a single dose of theophylline (4.3 mg/kg) delivered in 15 min using a constant-rate infusion pump, immediately before and after a 10 day course of miocamycin 17.5 mg/kg b.d.
N, Principi +3 more
exaly +3 more sources
Effects of Miocamycin and Erythromycin on Polymorphonuclear Cell Function
Journal of Chemotherapy, 1992Previous studies have shown that erythromycin can enter phagocytic cells, stimulating their functional activity. In this work we compared the effects of erythromycin and another newer macrolide antibiotic, miocamycin, on a series of in vitro tests aimed at evaluating their influence on polymorphonuclear cell (PMN) functions.
P. Bacci +5 more
exaly +4 more sources
Pharmacokinetics of Miocamycin Following Intravenous Administration to Cattle
Transboundary and Emerging Diseases, 2000The plasma pharmacokinetics for a single intravenous dose (10 mg/kg body weight) of miocamycin (a 16‐membered macrolide drug) was investigated in Holando Argentino cattle (n = 5). Blood drug concentrations were determined by a microbiological method and data were best‐fitted to a two‐compartment open model.
N J, Litterio +6 more
exaly +3 more sources
Kinetic Profile of Miocamycin in Middle Ear Fluid and Mucosa
Acta Oto-Laryngologica, 1991A group of 18 patients, before undergoing otoplastic surgery, was treated with miocamycin 600 mg in a single dose; middle ear tissue samples were collected at 2, 3, 4 and 6 h. A group of 20 patients suffering from secretory otitis media (SOM) was also treated with 600 mg of miocamycin in a single dose; collections of middle ear fluid (MEF) were ...
Francesco Scaglione
exaly +3 more sources
Miocamycin Distribution in Tonsillar and Pulmonary Tissues after Repeated Administration
Journal of Chemotherapy, 1990Twenty patients undergoing tonsillectomy were treated with a peroral administration of 600 mg of miocamycin every 12 hours for 4 days. On the 5th day, after a last administration of a dose of 600 mg the ablation of the tonsils was carried out on groups of 4 subjects, each one at the following times after oral intake of the drug: 2, 4, 6, 8, 12 h ...
Francesco Scaglione
exaly +3 more sources
Post-antibiotic effects of miocamycin, roxithromycin and erythromycin on Gram-positive cocci
International Journal of Antimicrobial Agents, 1993The 16-membered macrolide miocamycin (MOM) has been compared with the 14-membered compounds erythromycin and roxithromycin in terms of causing post-antibiotic effects (PAE). Five strains of methicillin-resistant Staphylococcus aureus, 3 Streptococcus pyogenes, 3 S.
J M, Hamilton-Miller, S, Shah
exaly +3 more sources

