Results 1 to 10 of about 275 (129)
Induction of the bioconversion of leucomycins by glucose and its regulation by butyrate. [PDF]
Agricultural and Biological Chemistry, 1979 Leucomycin A1 (LM A1) was converted to leucomycin A3 (LM A3) by Streptomyces kitasatoensis is glucose-containing medium. On the other hand, butyrate, one of the precursors of the aglycone, repressed the bioconversion of LM A1 to A3. The role of butyrate has been examined in connection with that of glucose. It was found that the production of the enzyme
Chiaki KITAO +2 more
core +4 more sources
STRUCTURE-BIOLOGICAL ACTIVITIES RELATIONSHIPS AMONG LEUCOMYCINS AND THEIR DERIVATIVES
The Journal of Antibiotics, 1968 The relationship between chemical structure and biological activity of leucomycins and their derivatives was examined in vivo and in vitro. The biological activity of Fr-group was higher than that of Ac-group in vitro, but the latter showed higher blood level and lower toxicity than Fr-group.
AKIHIRO MATSUMAE +7 more
core +4 more sources
Chemical and Pharmaceutical Bulletin, 1976 An aglycone moiety of leucomycin-A3 (1), leuconolide-A3-5, 18-hemiacetal (3), was isolated by the application of a modified Polonovski-reaction to leucomycin-A3 N-oxide (2). Two neutral macrolides, 2'-O-acetyl-3'-N-desdimethylamino-3'-oxo-leucomycin-A3 (5) and 2'-O-acetyl-3'-N-desmethyl-N-acetyl leucomycin-A3 (8) in which the mycaminose moiety of 1 was
NAKAGAWA
core +3 more sources
Chemischer Informationsdienst, 1976 AbstractChemistry of Leucomycins.
AKIRA NAKAGAWA +6 more
core +4 more sources
Chemistry of Leucomycins. VIII. Absolute Configuration of Leucomycin and Isoleucomycin
Chemical and Pharmaceutical Bulletin, 1970 AKIRA NAKAGAWA +6 more
core +3 more sources
The chemistry of the leucomycins. I. Partial structure of leucomycin A3
Tetrahedron Letters, 1967 Haruo Ogura, Satoshi Ōmura, Toju Hata
core +3 more sources
THE CHEMISTRY OF LEUCOMYCINS. VI
The Journal of Antibiotics, 1968 SATOSHI OMURA +2 more
core +3 more sources
Effect of leucomycins and analogues on binding [14C ]erythromycin to Escherichia coli ribosomes. [PDF]
Antimicrob Agents Chemother, 1974 Pestka S, Nakagawa A, Omura S.
europepmc +2 more sources
THE CHEMISTRY OF LEUCOMYCINS. IV
The Journal of Antibiotics, 1968 SATOSHI OMURA +2 more
core +3 more sources
The chemistry of the leucomycins. II. Structure and stereochemistry of leucomycin A3.
Tetrahedron Letters, 1967 Haruo Ogura, Satoshi Ōmura, Toju Hata
core +2 more sources