CircRNA circ-ATAD1 suppresses miR-618 maturation to participate in colorectal cancer [PDF]
BMC Gastroenterology, 2022 Background CircRNA circ-ATAD1 has been characterized as an oncogenic circRNA in gastric cancer, while its role in colorectal cancer (CRC) is unknown. This study was carried out to explore the role of circ-ATAD1 in CRC. Methods Paired CRC and adjacent non-
Li Cao, Guanglong Dong, Huan Li
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Circulating miR-618 Has Prognostic Significance in Patients with Metastatic Colon Cancer [PDF]
Current Oncology, 2021 The present study evaluated the prognostic role of circulating miRNA-618 in patients with metastatic colon cancer (mCC) and whether miR-618 gene rs2682818 single nucleotide polymorphisms (SNP) are associated with colon cancer susceptibility and ...
Maria Radanova +9 more
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Polymorphism rs2682818 participates in the progression of colorectal carcinoma via miR-618-TIMP1 regulatory axis [PDF]
Scientific Reports, 2021 Colorectal carcinoma (CRC) has a high morbidity and mortality. Current studies have confirmed a variety of microRNA polymorphisms were associated with tumor susceptibility, however, the mechanisms are still unknown.
Wei Shao +6 more
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MicroRNAs hsa-miR-618 and hsa-miR-297 Might Modulate the Pleiotropic Effects Exerted by Statins in Endothelial Cells Through the Inhibition of ROCK2 Kinase: in-silico Approach [PDF]
Frontiers in Cardiovascular Medicine, 2021 Several studies show that statin therapy improves endothelial function by cholesterol-independent mechanisms called “pleiotropic effects.” These are due to the inhibition of the RhoA/ROCK kinase pathway, its inhibition being an attractive ...
Karla Leal +3 more
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Association of single nucleotide polymorphisms in Pre-miR-27a, Pre-miR-196a2, Pre-miR-423, miR-608 and Pre-miR-618 with breast cancer susceptibility in a South American population. [PDF]
BMC Genet, 2016 Indexación: Web of ScienceBackground MicroRNAs (miRNAs) are a novel class of endogenous, non-coding, single-stranded RNAs capable of regulating gene expression by suppressing translation or degrading mRNAs.
Morales S +8 more
europepmc +7 more sources
MiR-618 suppresses the proliferation, invasion, and migration of non-small lung cancer via the JAK2/STAT3 axis [PDF]
Journal of Cardiothoracic SurgeryObjective The regulatory role of the miR-618/JAK2/STAT3 axis in non-small cell lung cancer cells (NSCLC) was investigated with the objective of identifying a target for the precise treatment of patients with NSCLC.
Ziyuan Chen +7 more
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miR-618: possible control over TIMP-1 and its expression in localized prostate cancer [PDF]
BMC Cancer, 2018 Background The imbalance between the action of the tissue inhibitors of matrix metalloproteinases (TIMPs) and the matrix metalloproteinases (MMPs) is one component of metastasis physiology. TIMP-1 overrides MMP-9 activity in cancer and might be regulated
Renato F. Ivanovic +9 more
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Polymorphism rs2682818 in miR‐618 is associated with colorectal cancer susceptibility in a Han Chinese population [PDF]
Cancer Medicine, 2018 MicroRNAs (miRNAs), endogenous small noncoding RNAs (ncRNAs), play crucial roles in cancer development. Many studies have demonstrated that miRNAs can serve as diagnostic and therapeutic biomarkers for malignancies.
Yuetong Chen +9 more
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Increased Expression of Circular RNA circ_0005230 Indicates Dismal Prognosis in Breast Cancer and Regulates Cell Proliferation and Invasion via miR-618/ CBX8 Signal Pathway [PDF]
Cellular Physiology and Biochemistry, 2018 Background/Aims: Circular RNAs (circRNAs) are a class of non-coding RNAs. They have been proved to be critically involved in tumorigenesis and progression of malignancies through competing endogenous RNA (ceRNA) mechanism.
Yi Xu +6 more
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Circulating extracellular vesicles as potential biomarkers and mediators of acute respiratory distress syndrome in sepsis [PDF]
Scientific ReportsThe early sequence of respiratory failure events after the onset of sepsis is still unknown. We hypothesize that the lung should signal through circulating extracellular vesicles (EVs) when it is affected by a systemic inflammatory response.
Marcelo Fernando do Nascimento +11 more
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