rs2682818/MiR-618 is a novel marker associated with increased risk of breast cancer in the Iranian population [PDF]
Archives of Biological Sciences, 2021 The presence of single nucleotide variations in the coding region of micro-RNA (miRNA)-encoding genes plays a significant role in the expression and function of these molecules in oncogenesis and cancer.
Najafian-Najafabady Atefeh +2 more
doaj +4 more sources
miR-618 rs2682818 C>A polymorphism decreases Hirschsprung disease risk in Chinese children. [PDF]
Biosci Rep, 2020 MicroRNAs (miRNAs) are endogenous non-coding small RNAs that play an important role in the development of many malignant tumors. In addition, recent studies have reported that single nucleotide polymorphisms (SNPs) located in the miRNA functional region ...
Zheng Y +5 more
europepmc +5 more sources
Inhibiting miR-618 Promotes Keratinocytes Proliferation and Migration to Enhance Wound Healing in Mice. [PDF]
Int J Mol SciThe delay in wound healing caused by chronic wounds or pathological scars is a pressing issue in clinical practice, imposing significant economic and psychological burdens on patients.
Wu L +10 more
europepmc +4 more sources
miR-618 Inhibits Prostate Cancer Migration and Invasion by Targeting FOXP2. [PDF]
J Cancer, 2017 miRNAs play critical role in the development and progression of prostate cancer. Here we studied the role of miR-618 in prostate cancer migration and invasion.
Song XL, Tang Y, Lei XH, Zhao SC, Wu ZQ.
europepmc +5 more sources
Long Non-Coding RNA HOTAIR Modulates KLF12 to Regulate Gastric Cancer Progression via PI3K/ATK Signaling Pathway by Sponging miR-618. [PDF]
Onco Targets Ther, 2019 Purpose Long non-coding RNA (lncRNA) HOX transcript antisense RNA (HOTAIR) has been reported to dysregulate in many tumors. However, the mechanism of HOTAIR was rarely reported in GC. Methods The levels of HOTAIR, microRNA-618 (miR-618) and Krueppel-like
Xun J, Wang C, Yao J, Gao B, Zhang L.
europepmc +5 more sources
Does miR-618 rs2682818 variant affect cancer susceptibility? Evidence from 10 case-control studies. [PDF]
Biosci Rep, 2019 Piles of evidence have supported the relationship between miR-618 rs2682818 polymorphism and tumorigenesis, but the conclusion remains inconsistent.
Feng X, Ji D, Liang C, Fan S.
europepmc +5 more sources
Targetome profiling and functional genetics implicate miR-618 in lymphomagenesis. [PDF]
Epigenetics, 2014 Despite the voluminous body of observational evidence concerning the role of miRNAs in cancer, significant knowledge gaps remain concerning the molecular circumstances that underlie the miRNA-cancer connection. In this study, we employ a multidisciplinary approach to establish an association between miR-618 and non-Hodgkin lymphoma (NHL) in a human ...
Fu A +5 more
europepmc +6 more sources
Circulating exosomal microRNA expression patterns distinguish cardiac sarcoidosis from myocardial ischemia. [PDF]
PLoS ONE, 2021 ObjectiveCardiac sarcoidosis is difficult to diagnose, often requiring expensive and inconvenient advanced imaging techniques. Circulating exosomes contain genetic material, such as microRNA (miRNA), that are derived from diseased tissues and may serve ...
Elliott D Crouser +8 more
doaj +3 more sources
Identification of aberrantly expressed lncRNAs and ceRNA networks in multiple myeloma: a combined high-throughput sequencing and microarray analysis [PDF]
Frontiers in Oncology, 2023 BackgroundThis study aimed to explore the potential effects of long non-coding RNAs (lncRNAs) in multiple myeloma (MM) patients using two detection methods: high-throughput sequencing and microarray.MethodsIn this study, lncRNAs were detected in 20 newly
Min-Qiu Lu +7 more
doaj +3 more sources
miR‐618 Suppresses Metastasis in Gastric Cancer by Downregulating the Expression of TGF‐β2 [PDF]
The Anatomical Record, 2019 Recent studies have demonstrated that microRNAs regulate gene expression and are related to cancer progression. Increasing evidence shows that miR‐618 plays an important role in a variety of tumors, including thyroid carcinomas, breast cancer and ...
Ji Shi +9 more
semanticscholar +3 more sources