Results 201 to 208 of about 2,947 (208)

CircRNACCDC66 regulates cisplatin resistance in gastric cancer via the miR-618/BCL2 axis

Biochemical and Biophysical Research Communications, 2020
Gastric cancer (GC) remains a serious threat to human health with a high cancer-related death rate and unsatisfactory treatment effects after curative resection, especially with advanced GC. Thus, exploration of the molecular mechanism of cisplatin (CDDP) resistance in GC is crucial. circCCDC66 (hsa_circ_0001313) expression was detected by quantitative
Qiang Zhang, Yongchang Miao, Qingsheng Fu, Hao Hu, Hao Chen, Ailiang Zeng, Yan Jin, Yangfan Jiang, Long Qian, Longchao Wu, Li Xu, Gang Wang, Lei Qiu, Xiaoxu Huang, Yabin Xia   +14 more
openaire   +2 more sources

Tanshinone IIA fromSalvia miltiorrhizaexerts anti‐fibrotic effects on cardiac fibroblasts and rat heart tissues by suppressing the levels of pro‐fibrotic factors: The key role of miR‐618

Journal of Food Biochemistry, 2022
Tanshinone IIA (TAN) is widely employed for handling cardiovascular disorders. The current study explored the potential role of miRs in the antifibrotic effect of TAN on heart. Fibrotic features were induced in cardiac fibroblasts (CFs) and in rat hearts, and then handled with TAN.
Na Yan, Chunqing Xiao, Xianggui Wang, Zufang Xu, Jiangyong Yang   +4 more
openaire   +2 more sources

MiR-618 inhibits anaplastic thyroid cancer by repressing XIAP in one ATC cell line

Annales d'Endocrinologie, 2014
X-linked inhibitor of apoptosis protein (XIAP) is a major factor in cancer growth and progression. Reduction of XIAP induces apoptosis of anaplastic thyroid cancer (ATC), which accounts for more than 50% of thyroid cancer mortality. MicroRNAs (miRNAs) are short non-coding RNA molecules, which modulate gene expression via interaction with mRNA by ...
Qianpeng, Cheng, Xingguang, Zhang, Xiuping, Xu, Xiaofeng, Lu   +3 more
openaire   +2 more sources

Correlation between the miR‐618 rs2682818 C>A polymorphism and venous malformation susceptibility

Biotechnology and Applied Biochemistry
AbstractVenous malformations are the most common congenital vascular malformations, and the incidence rate is high. Previous studies have confirmed that a variety of polymorphisms within the miRNA functional region are associated with tumor susceptibility.
Xi Lin, Zijian Chen, Guitao Wu, Hua Jiang, Zhenyin Liu   +4 more
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EIF4A3-induced circle RNA_ 0001860 promotes growth, invasion, and immune evasion of gastric cancer cells through the miR-618/HMGA2 axis

Neoplasma
Gastric cancer is a globally common type of cancer with a dismal prognosis. Circle RNA_ 0001860 (circ_0001860) is dysregulated in several cancers and involved in cancer development. Its involvement in stomach cancer, however, remains unclear. AGS and HGC-27 cells were transfected with shRNA against circ_0001860 to knock down the circ_0001860 level. The
Xiaoyi, Zhang, Jiaqi, Li, Qian, Zhang
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[Expression and function prediction of miR-618 in sputa and sera of patients with pulmonary tuberculosis].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2013
To measure the level of miR-618 in sputa and sera from the patients with pulmonary tuberculosis, determine the concentration of IL-13 which is a cytokine encoded by target gene of miR-618, and predict the function of miR-618 with bioinformatics.Sputum and serum samples were collected from the healthy controls and the patients with active pulmonary ...
Zhengjun, Yi, Yurong, Fu, Hongjuan, Wu, Shan, Zhao   +3 more
openaire   +1 more source

Genetic variant in miR-618 in the risk of chronic lymphocytic leukemia

European Journal of Cancer, 2016
I. Martín-Guerrero, A. Díaz-Navarro, A. Gutierrez-Camino, A. Garcia-Orad   +3 more
openaire   +1 more source

Validation of gene polymorphisms (rs2682818 and rs2043556) in has-miR-618 and has-miR-605 with the breast cancer susceptibility

Human Gene
Arvin Hassani, Saeid Ghorbian
openaire   +1 more source