Dexmedetomidine alleviates high glucose-induced podocyte damage by inhibiting EDA2R [PDF]
, 2022 Purpose: To investigate the effect and mechanism of action of dexmedetomidine (Dex) on podocyte injury. Methods: Cells were incubated with high glucose (50 mM) to induce a podocyte injury model in vitro.
Chen, Xiang +3 more
core +2 more sources
The function of miR-218 and miR-618 in postmenopausal osteoporosis.
European review for medical and pharmacological sciences, 2017 Postmenopausal osteoporosis (POMP) is a serious disorder with significant physical, psychosocial, and financial consequences, which greatly reduce the postmenopausal women's life quality. The related issues of postmenopausal osteoporosis are increasingly concerned by society.
Wang, W.-W. +6 more
openaire +2 more sources
Differential expression of miR-145 in children with Kawasaki disease. [PDF]
PLoS ONE, 2013 Kawasaki disease is an acute, self-limited vasculitis of childhood that can result in structural damage to the coronary arteries. Previous studies have implicated the TGF-β pathway in disease pathogenesis and generation of myofibroblasts in the arterial ...
Chisato Shimizu +10 more
doaj +1 more source
Altered microRNA and target gene expression related to Tetralogy of Fallot [PDF]
, 2019 MicroRNAs (miRNAs) play an important role in guiding development and maintaining function of the human heart. Dysregulation of miRNAs has been linked to various congenital heart diseases including Tetralogy of Fallot (TOF), which represents the most ...
Appelt, Sandra +4 more
core +2 more sources
miRNA signature predittivo di metastasi linfonodali da carcinoma della laringe [PDF]
, 2017 The discovery that miRNAs are frequently deregulated in tumours offers the opportunity to identify them as prognostic and diagnostic markers. The aim of this multicentric study is to identify a miRNA expression profile specific for laryngeal cancer.
Abate, T. +10 more
core +1 more source
Pathogenetic and diagnostic significance of microRNA deregulation in peripheral T-cell lymphoma not otherwise specified [PDF]
, 2014 Peripheral T-cell lymphomas not otherwise specified (PTCLs/NOS) are rare and aggressive tumours whose molecular pathogenesis and diagnosis are still challenging.
Agostinelli, C. +22 more
core +3 more sources
Frontiers in Endocrinology, 2019 Objective: To compare the serum micro-RNAs (miRNAs) profile of individuals with type 1 diabetes without microvascular complications vs. those with multiple severe microvascular complications, in order to identify epigenetically modulated pathways in ...
Daniele P. Santos-Bezerra +13 more
doaj +1 more source
The effect of COVID-19 on micro RNA and therefore gene expression [PDF]
, 2022 After the scourge of the coronavirus invaded almost all of the world, they were infected with this epidemic, and therefore this has caused changes and variations within the corridors of living cells, which have transgressed to some organs and even ...
Alquraishi, Mohammed. K. S. +1 more
core +2 more sources
Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria [PDF]
, 2016 Malaria remains one of the greatest public health challenges worldwide, particularly in sub-Saharan Africa. The clinical outcome of individuals infected with Plasmodium falciparum parasites depends on many factors including host systemic inflammatory ...
A Bhoumik +64 more
core +1 more source
Effect of rPMS on N-type calcium channel in rats with neuropathic pain [PDF]
, 2022 Purpose: To investigate the effect of repetitive peripheral magnetic stimulation (rPMS) on N-type calcium channel of rats with neuropathic pain (NP). Methods: Thirty-two Sprague-Dawley (SD) rats were randomized into control, mock surgical, model, and ...
Cai, Xianbin, Xu, Xuefen
core +2 more sources