Analysis of Differentially Expressed MicroRNAs in Serum and Lung Tissues from Individuals with Severe Asthma Treated with Oral Glucocorticoids [PDF]
Biomarker; Individuals with severe asthma; Oral corticosteroidsBiomarcador; Persones amb asma greu; Corticosteroides oralsBiomarcador; Personas con asma grave; Corticosteroides oralesNowadays, microRNAs (miRNAs) are increasingly used as biomarkers due to
Cruz Carmona, Mª Jesús +7 more
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T‐cell prolymphocytic leukemia is associated with deregulation of oncogenic microRNAs on transcriptional and epigenetic level [PDF]
Deregulation of micro(mi)-RNAs is a common mechanism in tumorigenesis. We investigated the expression of 2083 miRNAs in T-cell prolymphocytic leukemia (T-PLL). Compared to physiologic CD4+ and CD8+ T-cell subsets, 111 miRNAs were differentially expressed
Bens, Susanne +22 more
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Genetic Variants in miRNAs Are Associated With Risk of Non-syndromic Tooth Agenesis
Non-syndromic tooth agenesis (NSTA) is one of the most common dental abnormalities. MiRNAs participated in the craniofacial and tooth development. Therefore, single nucleotide polymorphisms (SNPs) in miRNA genes may contribute to the susceptibility of ...
Min Gu +19 more
doaj +1 more source
microRNA. Diagnostic Perspective [PDF]
Biomarkers are biological measures of a biological state. An ideal marker should be safe and easy to measure, cost efficient, modifiable with treatment, and consistent across gender and ethnic groups. To date, none of the available biomarkers satisfy all
FARUQ, MD OMAR, VECCHIONE, ANDREA
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Dexmedetomidine alleviates high glucose-induced podocyte damage by inhibiting EDA2R [PDF]
Purpose: To investigate the effect and mechanism of action of dexmedetomidine (Dex) on podocyte injury. Methods: Cells were incubated with high glucose (50 mM) to induce a podocyte injury model in vitro.
Chen, Xiang +3 more
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Altered microRNA and target gene expression related to Tetralogy of Fallot [PDF]
MicroRNAs (miRNAs) play an important role in guiding development and maintaining function of the human heart. Dysregulation of miRNAs has been linked to various congenital heart diseases including Tetralogy of Fallot (TOF), which represents the most ...
Appelt, Sandra +4 more
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miRNA signature predittivo di metastasi linfonodali da carcinoma della laringe [PDF]
The discovery that miRNAs are frequently deregulated in tumours offers the opportunity to identify them as prognostic and diagnostic markers. The aim of this multicentric study is to identify a miRNA expression profile specific for laryngeal cancer.
Abate, T. +10 more
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Pathogenetic and diagnostic significance of microRNA deregulation in peripheral T-cell lymphoma not otherwise specified [PDF]
Peripheral T-cell lymphomas not otherwise specified (PTCLs/NOS) are rare and aggressive tumours whose molecular pathogenesis and diagnosis are still challenging.
Agostinelli, C. +22 more
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The effect of COVID-19 on micro RNA and therefore gene expression [PDF]
After the scourge of the coronavirus invaded almost all of the world, they were infected with this epidemic, and therefore this has caused changes and variations within the corridors of living cells, which have transgressed to some organs and even ...
Alquraishi, Mohammed. K. S. +1 more
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Objective: To compare the serum micro-RNAs (miRNAs) profile of individuals with type 1 diabetes without microvascular complications vs. those with multiple severe microvascular complications, in order to identify epigenetically modulated pathways in ...
Daniele P. Santos-Bezerra +13 more
doaj +1 more source

