The contribution of epigenetics to the pathogenesis and gender dimorphism of systemic sclerosis: a comprehensive overview [PDF]
Systemic sclerosis (SSc) is a life-threatening connective tissue disorder of unknown etiology characterized by widespread vascular injury and dysfunction, impaired angiogenesis, immune dysregulation and progressive fibrosis of the skin and internal ...
Fioretto, Bianca Saveria +7 more
core +1 more source
Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast [PDF]
Micropapillary carcinoma ( MPC ) is a rare histological special type of breast cancer, characterized by an aggressive clinical behaviour and a pattern of copy number aberrations ( CNAs ) distinct from that of grade‐ and oestrogen receptor ( ER )‐matched ...
A'hern, Roger +26 more
core +3 more sources
Importance of MicroRNAs in Hepatitis B and C Diagnostics and Treatment [PDF]
MicroRNAs (miRNAs) are small‐sized RNAs with ability to regulate gene expression and have been recently discovered as promising diagnostic and therapeutic biomarkers in the field of clinical medicine and microbiology, specifically in viral diseases ...
Glavač, Damjan, Jelen, Mateja M.
core +2 more sources
LncRNA CERS6-AS1, sponging miR-6838-5p, promotes proliferation and invasion in cervical carcinoma cells by upregulating FOXP2 [PDF]
Cervical cancer (CC) is a common disease in women characterized by high recurrence rate. LncRNA ceramide synthase 6 antisense RNA 1 (CERS6-AS1) has been found to play a crucial role in the progression of breast cancer and pancreatic cancer ...
Chu, Guanghua +6 more
core
Ethnicity and the surgical management of early invasive breast cancer in over 164 000 women
This large national study examined in detail the patterns in surgical management of early breast cancer in women of different ethnicities. Allowing for different patterns of age and stage at presentation, the surgical management of early breast cancer was similar in all women, regardless of ethnicity. All treated the same Background Limited information
T. Gathani +4 more
wiley +1 more source
Genome-wide comparative analysis of microRNAs in three non-human primates [PDF]
Background MicroRNAs (miRNAs) are negative regulators of gene expression in multicellular eukaryotes. With the recently completed sequencing of three primate genomes, the study of miRNA evolution within the primate lineage has only begun and may be ...
A Nahvi +25 more
core +3 more sources
Clean Cut is a multimodal, adaptive, checklist‐based infection prevention programme designed to improve compliance with six critical perioperative infection prevention practices. After introducing the programme at five hospitals in Ethiopia, compliance with critical infection prevention standards significantly improved and the relative risk of ...
J. A. Forrester +16 more
wiley +1 more source
Roles of the hox proteins in cancer invasion and metastasis [PDF]
Invasion and metastasis correspond to the foremost cause of cancer-related death, and the molecular networks behind these two processes are extremely complex and dependent on the intra-and extracellular conditions along with the prime of the ...
Costa-Pinto, AR +4 more
core +1 more source
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren's disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr +5 more
wiley +1 more source
Is tissue still the issue? The promise of liquid biopsy in uveal melanoma [PDF]
Uveal melanoma (UM) is the second most frequent type of melanoma. Therapeutic options for UM favor minimally invasive techniques such as irradiation for vision preservation. As a consequence, no tumor material is obtained.
Beasley, Aaron B. +10 more
core +3 more sources

