Results 71 to 80 of about 2,947 (208)

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

A Parallel Study of mRNA and microRNA Profiling of Peripheral Blood in Young Adult Women [PDF]

, 2011
Background: Aging is a complex process that involves the interplay of genetic, epigenetic, and environmental factors. Identifying aging-related biomarkers holds great potential for improving our understanding of complex physiological changes, thereby ...
Gadd, Samantha, Huang, Chiang-Ching, Jafari, Nadereh, Sredni, Simone T.   +3 more
core   +3 more sources

A smart headband for multimodal physiological monitoring in human exercises

Advanced Science, EarlyView.
A novel smart headband incorporating a thermal‐sensation‐based electronic skin is presented for continuous and accurate multimodal physiological monitoring, including pulse waveforms, total metabolic energy expenditure, heart rate, and forehead temperature, across both static and dynamic daily activities.
Shiqiang Liu, Guanxing Chen, Jingyi Peng, Shuo Tian, Qian Mao, Caise Wei, Jinfeng Yuan, Rong Zhu   +7 more
wiley   +1 more source

Prognostic Impact of Histologic Subtypes in Mismatch Repair‐Deficient/Microsatellite Instability‐High Colorectal Cancer: A Single‐Center Retrospective Study of 1127 Stage 0–IV Patients

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Deficient mismatch repair/microsatellite instability‐High (dMMR/MSI‐H) colorectal cancer (CRC) generally confers a favorable survival yet is paradoxically enriched for poorly differentiated (Por) histology, which is linked to aggressive behavior.
Tomoyuki Momma, Hirokazu Okayama, Sohei Hayashishita, Hiroya Suzuki, Masanori Katagata, Takuro Matsumoto, Daisuke Ujiie, Shun Chida, Wataru Sakamoto, Koji Kono   +9 more
wiley   +1 more source

Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood [PDF]

, 2010
Background MicroRNAs are a class of small non-coding RNAs that regulate mRNA expression at the post - transcriptional level and thereby many fundamental biological processes.
Ahmad, Hafiz M, Bhattacharya, Alok, Gupta, Rashi, Kulshreshtha, Ritu, Kumar, Lalit, Sharma, Pratibha, Vaz, Candida   +6 more
core   +3 more sources

Healthcare Resource Utilization and Cost After Temperature‐Controlled Radiofrequency Treatment of Nasal Airway Obstruction: A Real‐World Longitudinal Claims Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Nasal airway obstruction (NAO) is prevalent with substantial health and quality of life burdens. Nasal valve collapse (NVC) is one structural cause of NAO. Temperature‐controlled radiofrequency (TCRF) nasal valve remodeling offers an alternative to invasive surgery.
David W. Kennedy, Gavin Setzen, Ashleigh A. Halderman, Kevin C. Welch, Bobby Tajudeen, Gary M. Owens, Paul J. Niklewski, Masayoshi Takashima   +7 more
wiley   +1 more source

An Examination of Racial Bias in Scoring the Autism Diagnostic Observation Schedule (ADOS) Module 3: An Item Response Theory Analysis

Autism Research, EarlyView.
ABSTRACT Given the rising prevalence of autism among racial minority children in the United States, but persistent service use disparities, this study examines potential bias in specific items from the autism diagnostic observation schedule (ADOS), a highly regarded autism evaluation.
Yuen Yvonne Yu, Austin Wyman, Calliana J. Faulk, Lizzy J. Fulop, Rebecca L. Greenberg, Rachel M. Benecke, Lauren K. Steinbeck, Jessica Foy, Caitlyn Kim, George O. Emory, Eric A. Storch, Casey J. Zampella, Benjamin E. Yerys, Robert T. Schultz, Julia Parish‐Morris, John D. Herrington, Caitlin C. Clements   +16 more
wiley   +1 more source

Psychoactive prescription drug use and misuse in patients on opioid agonist treatment

British Journal of Clinical Pharmacology, EarlyView.
Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro, Clémence Lacroix, Élisabeth Jouve, Élisabeth Frauger, Maryse Lapeyre‐Mestre, Joëlle Micallef   +5 more
wiley   +1 more source

MicroRNA dysregulation in colorectal cancer: a clinical perspective [PDF]

Recent researches have shed light on the biological importance of microRNAs (miRNAs) in colorectal cancer (CRC) genesis, progression and response to treatments. The potential utility of miRNAs in the preclinical stage have been explored and investigated.
A Link, AJ Schetter, B Song, C W Wu, CJ Wang, CW Wu, D Landi, DA Ahlquist, DA Lieberman, DP Bartel, E Bandrés, EK Ng, EM Kroh, FE Ahmed, FE Ahmed, G Lanza, G Nakajima, GA Calin, HC Lee, J Ferlay, J J Y Sung, J Yu, JS Earle, K Chen, K Motoyama, M Idogawa, M Ragusa, M Svoboda, N Kosaka, O Slaby, PS Mitchell, R Díaz, R Yang, S S M Ng, SA Melo, SE Wojcik, T Schepeler, V Boni, V Kulda, W K K Wu, X Chen, Y Dong, Y Koga, Z Huang, Z Yu   +44 more
core   +2 more sources

Pharmacokinetics, pharmacodynamics and safety of vutiglabridin after multiple oral administrations in healthy female and obese subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims Vutiglabridin (HSG4112) is a novel drug under clinical development for antiobesity treatment. This study aimed to evaluate the pharmacokinetics (PKs) and safety of vutiglabridin after multiple oral administrations in healthy Korean female and obese subjects and explore short‐term pharmacodynamic (PD) responses.
Sooyoun Lee, Hyun Chul Kim, Young Ran Yoon, In‐Jin Jang, Sang‐Ku Yoo, Kyung‐Sang Yu   +5 more
wiley   +1 more source