Results 81 to 90 of about 315,174 (223)

Combined Gravimetric, Electrochemical, and Computational Research on Benzothiophene Derivatives as Effective Corrosion Inhibitors for Mild Steel

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Four benzothiophenes, thianaphthene (BT‐1), 3‐bromothianaphthene (BT‐2), benzo[b]thiophene‐2‐carboxaldehyde (BT‐3), and benzo[b]thiophene‐2‐carbonitrile (BT‐4), were tested as mild steel corrosion inhibitors in 1‐M HCl. The compounds have the similar benzothiophene core but differ in the substituents bound to the ring.
Nhlanhla G. Chirwa, Motsie Elija Mashuga, Mohammad Salman, Indra Bahadur   +3 more
wiley   +1 more source

Zooarchaeological Analysis of an Atoll Assemblage From Central Micronesia

Archaeology in Oceania, EarlyView.
ABSTRACT There has been a dearth of archaeological research on atolls in the central‐eastern Caroline Islands of Micronesia. This has limited our understanding of pre‐contact subsistence and settlement strategies in these more marginal and remote environments, particularly in regards to zooarchaeological data.
Philippa Jorissen, Gabriel Sanchez, Scott M. Fitzpatrick   +2 more
wiley   +1 more source

Single‐cell level characterization of B cell depletion and repopulation following rituximab in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang, Norzawani Buang, Catherine Sutherland, Wanseon Lee, Lauren Overend, Tarran S. Rupall, Katie L. Burnham, Matthew C. Pickering, Marina Botto, Emma E. Davenport   +9 more
wiley   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Activation of microRNA-596 induced by DNA demethylation and interferon in malignant melanoma cells [PDF]

, 2017
Dysregulation of microRNA has been implicated in melanoma, although the mechanism is not fully understood. We aimed to examine the epigenetically silenced miRNAs and its involvement in the antitumor effect of DNA demethylation and interferon in melanoma.
Akihiro, YONETA, Eiichiro, YAMAMOTO, Hiromu, SUZUKI, Masahiro, KAI, Masami, ASHIDA, Minoru, TOYOTA, Reo, MARUYAMA, Takahiro, NISHIZAKA, Takashi, TOKINO, Tokimasa, HIDA, Toshiharu, YAMASHITA   +10 more
core   +1 more source

‘These reforms have teeth’: The affective dimensions of teacher education policy enactment

British Educational Research Journal, EarlyView.
Abstract The affective dimensions of education policy enactment have often received less attention in the research literature, especially regarding teacher education policy. This article reports on a study of the affective responses of university‐based teacher educators in England to the significant initial teacher education reforms of 2019–2022: the ...
Ian Cushing, Viv Ellis
wiley   +1 more source

Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis? [PDF]

, 2018
Background: Exosomes isolated from plasma of patients with sepsis may induce vascular apoptosis and myocardial dysfunction by mechanisms related to inflammation and oxidative stress.
Azevedo, Luciano Cesar Pontes, Bezerra-Neto, Joao Evangelista, Cunha-Neto, Edecio, Dias, Marcos Vinicius Salles, Esteves, Gustavo Henrique, Ferreira, Ludmila Rodrigues Pinto, Koyama, Fernanda Christtanini, Machado, Flavia Ribeiro, Real, Juliana Monte, Salomão, Reinaldo   +9 more
core   +2 more sources

Trithio‐naphthalic anhydride‐based photosensitizer for photodynamic activity

Bulletin of the Korean Chemical Society, EarlyView.
A trithio‐naphthalic anhydride photosensitizer (NapS) is created by simple thionation, switching excited‐state pathways to deliver both type I and type II reactive oxygen species. NapS enables efficient photodynamic therapy under normoxia and hypoxia, achieving strong cancer cell killing with low dark toxicity.
Thanh Chung Pham, Thuy Kieu Van Nguyen, Lei Cao, Sondavid Nandanwar, Yeonghwan Choi, Sanggil Lee, Songyi Lee   +6 more
wiley   +1 more source

Sequential, chromosome‐specific glutamine synthetase double knockout with Cas‐CLOVER establishes enhanced CHO platforms for cell line development

Biotechnology Progress, EarlyView.
This study established the first creation of a commercially available double GS knockout (DKO) from a single KO in CHO‐K1 cells, called CleanCut GS CHO using Cas‐CLOVER. When combined with the Harbor‐IN transposase system, CleanCut GS CHO cells demonstrated a highly antibody productivity.
Cintia Gomez Limia, Valeriya Steffey, Hsueh Che Cheng, Daniel Machado, Thomas Hart, Mark Cameron McHargue, Corey Brizzee, Jack Crawford   +7 more
wiley   +1 more source

Oxophilicity‐Driven Potential Window Engineering Enables Scalable and Low‐Emission Paired Electrosynthesis on Asymmetric CuOx@Ag Platform

Carbon and Hydrogen, EarlyView.
An asymmetric CuOx@Ag electrocatalyst platform enables paired electrochemical valorization of glycerol and 4‐nitrophenol, while effectively decoupling both half‐reactions from OER and HER. Ag‐mediated surface engineering expands the potential window and boosts reaction selectivity, achieving > 90% Faradaic efficiencies at both electrodes.
Xulai Gong, Linjie Zhao, Yongde Long, Hongwu Chen, Jiaxin Bai, Lei Chao, Xinyou Han, Baoguang Mao, Xianwei Liu, Yuanqing Shen, Wei Liu, Bowen Liu, Husitu Lin, Yang Song, Chuangang Hu   +14 more
wiley   +1 more source