Results 41 to 50 of about 3,535 (191)

Assessment of Codispensing Patterns of Mirabegron and Prespecified CYP2D6 Substrates in Patients with Overactive Bladder

Drugs - Real World Outcomes, 2023
Background Patients with overactive bladder (OAB) experience sudden, intense urges to urinate, which may include urge urinary incontinence and nocturia.
Jingjun Wang, Mary E. Ritchey, Kamika Reynolds, Madeleine Carbonneau, Adam Carrera, Noelia Goti, John R. Horn, Cynthia J. Girman   +7 more
doaj   +1 more source

Possible Effects of Mirabegron on Rat Liver in Renal Ischemia Reperfusion Injury: Histological and Immunohistochemical Studies [PDF]

Minia Journal of Medical Research, 2020
Liver and kidney are both critical controller organs in our body and any liver or kidney damage including organ ischemia, may affect the other. Renal ischemia reperfusion injury diminishes antioxidant protein and increases neutrophils and lymphocytes ...
Mahmoud Montaser, Ibrahim . K Ragab, Esam Kamel   +2 more
doaj   +1 more source

Mirabegron displays anticancer effects by globally browning adipose tissues

, 2023
Metabolic reprogramming in malignant cells is a hallmark of cancer that relies on augmented glycolytic metabolism to support their growth, invasion, and metastasis. However, the impact of global adipose metabolism on tumor growth and the drug development
Jieyu Wu, Sisi Xie, Sen Li, Yunlong Yang, Xu Jing, Wenhai Sui, Jinxiu Deng, Ping Huang, Takahiro Seki, Xiaokun Li, Zepeng Mu, Yangang Wang, Yihai Cao, Xiaoting Sun, Minghua Ge, Xingkang He, Deng, J, He, X, Xie, S, Seki, T,, Jing, X,, Sui, W, Wu, J, Mu, Z, Sun, X, Li, S   +25 more
core   +1 more source

Mirabegron and solifenacin are effective for the management of the increased urinary frequency induced by psychological stress in female mice

Scientific Reports, 2022
Evidence to support the effectiveness of β3-adrenoceptor agonist mirabegron and anti-muscarinic solifenacin in the management of bladder dysfunction caused by psychological stress is lacking.
Eliza G. West, Catherine McDermott, Russ Chess-Williams, Donna J. Sellers   +3 more
doaj   +1 more source

Comparison of Two Different Drugs for Overactive Bladder, Solifenacin and Mirabegron: A Prospective Randomized Crossover Study [PDF]

, 2019
To assess the efficacy and safety of 2 drugs for overactive bladder (OAB), solifenacin and mirabegron. Fortyseven female OAB patients were randomized into 2 groups.
Inoue, Miyabi, Yokoyama, Teruhiko
core   +1 more source

Mirabegron in Overactive Bladder and Its Role in Exit Strategy After Botulinum Toxin Treatment in Children

Frontiers in Pediatrics, 2022
PurposeMirabegron is a recent addition to the management options of overactive bladder (OAB) in children. The purpose of this study was to ascertain the role of Mirabegron in the treatment algorithm of therapy-resistant OAB especially after botulinum ...
Denise Jia Yun Tan, Julia Weninger, Anju Goyal   +2 more
doaj   +1 more source

Efficacy of adding mirabegron to alpha-adrenoreceptor blocker in patients with benign prostatic hyperplasia with persistent overactive bladder symptoms: A prospective study [PDF]

Investigative and Clinical Urology, 2020
Purpose: To compare the efficacies of mirabegron 50 mg addition after alpha-adrenoreceptor blocker in terms of reducing storage symptoms in patients with BPH.
Se Yun Kwon , Dong Jin Park , Young Jin Seo, Kyung Seop Lee   +3 more
doaj   +1 more source

Mirabegron, a Selective β3-Adrenergic Receptor Agonist, as a Potential Anti-Obesity Drug

, 2023
Obesity is becoming a global health epidemic. Brown and “beige” adipose tissue may produce heat, leading to energy expenditure enhancement and weight loss.
Jarosław Dudka, Anna Maria Dąbrowska
core   +1 more source

CYP2D6 Substrate Dispensing Among Patients Dispensed Mirabegron: An Administrative Claims Analysis

Drugs - Real World Outcomes, 2022
Background Overactive bladder (OAB) is characterized by the presence of bothersome urinary symptoms. Pharmacologic treatment options for OAB include anticholinergics and β3-adrenergic agonists.
Mary E. Ritchey, Jingjun Wang, Jessica C. Young, Rajat Chandra, Adam Carrera, Noelia Goti, John R. Horn, Cynthia J. Girman   +7 more
doaj   +1 more source

Efficacy of mirabegron for ureteral stones: a systematic review with meta-analysis of randomized controlled trials

Frontiers in Pharmacology, 2023
Background: Medical expulsive therapy demonstrates efficacy in managing ureteral stones in patients amenable to conservative interventions. This meta-analysis aims to evaluate the effectiveness of mirabegron in the treatment of ureteral stones.Methods ...
Zhenguo Wang, Junpeng Chi, Yuhua Liu, Jitao Wu, Yuanshan Cui, Chenchen Yang   +5 more
doaj   +1 more source