Results 271 to 280 of about 352,606 (330)

Ancestral allele of DNA polymerase gamma modifies antiviral tolerance. [PDF]

Nature
Kang Y, Hepojoki J, Maldonado RS, Mito T, Terzioglu M, Manninen T, Kant R, Singh S, Othman A, Verma R, Uusimaa J, Wartiovaara K, Kareinen L, Zamboni N, Nyman TA, Paetau A, Kipar A, Vapalahti O, Suomalainen A.   +18 more
europepmc   +1 more source

First‐In‐Human Safety, Pharmacokinetics, and Pharmacodynamics of VENT‐02 Freebase, a CNS‐Penetrant NLRP3 Inhibitor

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT The NLRP3 inflammasome is a central mediator of innate immunity and a key driver of inflammatory and neurodegenerative diseases. VENT‐02 is orally bioavailable, central nervous system‐penetrant, selective small‐molecule inhibitor of NLRP3. This first‐in‐human, randomized, double‐blind, placebo‐controlled study assessed the safety, tolerability,
Lisanne C. A. Smidt, Matthijs Moerland, Manon A. A. Jansen, Philip H. C. Kremer, Alexandra A. J. Sille, Pamela K. Strugala, Erica S. Klaassen, Anick Auger, Silvana Jananji, Rania Faidi, Kelly A. Pike, Loraine Warner, Andre Matta, Xavier Valencia, Ofer Spiegelstein   +14 more
wiley   +1 more source

GLP-1 receptor agonists as an adjunct to bariatric surgery for weight loss and metabolic outcome improvement: a systematic review and meta-analysis. [PDF]

Langenbecks Arch Surg
Tan YW, Shang M, Davis S, Gananadha S.
europepmc   +1 more source

Acute intraocular pressure responses changes during dynamic resistance training in primary open-angle glaucoma patients and age-matched controls. [PDF]

Graefes Arch Clin Exp Ophthalmol
Morenas-Aguilar MD, González-Hernández C, Marcos-Frutos D, Miras-Moreno S, López-Gómez MJ, García-Ramos A, Vera J.   +6 more
europepmc   +1 more source

Respiratory syncytial virus-related lower respiratory tract infection hospitalizations in infants receiving nirsevimab in Galicia (Spain): the NIRSE-GAL study. [PDF]

Eur J Pediatr
Manzanares A, Pardo-Seco J, Rivero-Calle I, Dacosta-Urbieta A, Mallah N, Santiago-Pérez MI, Pérez-Martínez O, Otero-Barrós MT, Suárez-Gaiche N, Kramer R, Jin J, Platero-Alonso L, Alvárez-Gil RM, Ces-Ozores OM, Nartallo-Penas V, Mirás-Carballal S, Piñeiro-Sotelo M, González-Pérez JM, Rodríguez-Tenreiro-Sánchez C, Salas A, Durán-Parrondo C, Martinón-Torres F.   +21 more
europepmc   +1 more source

Phenotyping and metabolomics insights into the effect of melatonin in lettuce under non-stress and salinity conditions. [PDF]

Physiol Plant
Secomandi E, Senizza B, De Gregorio MA, Miras-Moreno B, Rivero RM, Garcia-Perez P, Lucini L.   +6 more
europepmc   +1 more source

Author Correction: Chemical disinfection as a simple and reliable method to control the amphibian chytrid fungus at breeding points of endangered amphibians. [PDF]

Sci Rep
Thumsová B, González-Miras E, Rubio Á, Granados I, Bates KA, Bosch J.   +5 more
europepmc   +1 more source

Issue Information

Journal of the World Aquaculture Society, Volume 57, Issue 3, June 2026.
wiley   +1 more source

Social Determinants as Mediators of the Emotional State of People With Type 2 Diabetes and/or Hypertension During the COVID-19 Pandemic in Ecuador and Spain. [PDF]

Health Expect
Sanchís-Ramón MJ, Chilet-Rosell E, Peralta A, Puig-García M, Rivadeneira MF, Caicedo C, Benazizi-Dahbi I, Lumbreras B, Nicols M, Cebrián A, Ricart W, Lopez-Miras E, Parker LA.   +12 more
europepmc   +1 more source

Effect of the Stretch-Shortening Cycle on the Relationship Between Maximum Number of Repetitions and Lifting Velocity During the Prone Bench Pull. [PDF]

Sports Health
Miras-Moreno S, García-Ramos A, Weakley J, Rojas-Ruiz FJ, Pérez-Castilla A.   +4 more
europepmc   +1 more source