Results 11 to 20 of about 160 (158)

Expression of miR-302a, miR-302b, miR-302c, miR-302d, miR-367, miR-371, miR-372, miR-373, miR-10b, miR-21 and miR-93 in cells of different histotypes of testicular germ cell tumors

Advances in Molecular Oncology, 2022
Introduction. Testicular germ cell tumor is a relatively rare disease. Its high social significance is due to the fact that this pathology occurs in young patients. The standard schemes of polychemotherapy determine the potential possibility of effective treatment for most of the patients even with an advanced disease.
M. S. Knyazeva, V. A. Zagoruiko, A. V. Khokhlova, I. V. Nazarova, A. V. Shalaev, E. I. Sidina, L. M. Zabegina, A. S. Artemyeva, A. K. Nosov, S. A. Protsenko, A. V. Malek   +10 more
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Genetic Variants miR-126, miR-146a, miR-196a2, and miR-499 in Polycystic Ovary Syndrome [PDF]

British Journal of Biomedical Science, 2022
Introduction: Alterations in certain microRNAs (miRNAs) and their target genes have reported in polycystic ovary syndrome (PCOS) and other disease of the female reproductive system, and so may be potential biomarkers. We hypothesised alterations in the prevalence of four miRNAs single nucleotide polymorphism (SNP) variants miR-126 rs4636297, miR-146a ...
Li, R., Yu, Y., Jaafar, S. O., Baghchi, B., Farsimadan, M., Arabipour, I., Vaziri, H.   +6 more
openaire   +2 more sources

Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer [PDF]

BMC Cancer, 2012
MicroRNAs (miRNAs) regulate gene expression by binding to mRNA, and can function as oncogenes or tumor suppressors depending on the target. In this study, using qRT-PCR, we examined the expression of six miRNAs (miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145) in tumors from 193 prospectively recruited patients with colorectal cancer, and ...
Schee Kristina, Boye Kjetil, Abrahamsen Torveig, Fodstad Øystein, Flatmark Kjersti   +4 more
openaire   +3 more sources

Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients [PDF]

British Journal of Cancer, 2015
Owing to late diagnosis in advanced disease stages, prognosis of patients with epithelial ovarian cancer (EOC) is poor. The quantification of deregulated levels of microRNAs could facilitate earlier diagnosis and improve prognosis of EOC.Seven microRNAs (miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429) were quantified in the serum of 180 ...
Xiaodan Meng, Simon A Joosse, Volkmar Müller, Fabian Trillsch, Karin Milde-Langosch, Sven Mahner, Maria Geffken, Klaus Pantel, Heidi Schwarzenbach   +8 more
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miR-1, miR-10b, miR-155, and miR-191 are novel regulators of BDNF [PDF]

Cellular and Molecular Life Sciences, 2014
Brain-derived neurotrophic factor (BDNF) is a secreted protein of the neurotrophin family that regulates brain development, synaptogenesis, memory and learning, as well as development of peripheral organs, such as angiogenesis in the heart and postnatal growth and repair of skeletal muscle.
Varendi, Kärt, Kumar, Anmol, Härma, Mari-Anne, Andressoo, Jaan-Olle   +3 more
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miR‐17, miR‐19b, miR‐20a, and miR‐106a are down‐regulated in human aging [PDF]

Aging Cell, 2010
SummaryAging is a multifactorial process where deterioration of body functions is driven by stochastic damage while counteracted by distinct genetically encoded repair systems. To better understand the genetic component of aging, many studies have addressed the gene and protein expression profiles of various aging model systems engaging different ...
Strasser, A., Trost, A., Grubeck-Loebenstein, B., Mück, C., Papak, C., Schreiner, C., Herndler-Brandstetter, D., Tschachler, E., Laschober, G., Lepperdinger, G., Kühnel, H., Grillari, J., Bauer, J.W., Fortschegger, K., Eckhard, L., Micutkova, L., Breitenbach, M., Hackl, M., Mildner, M., Rinnerthaler, M., Scheideler, M., Wieser, M., Sampson, N., Berger, P., Jansen-Dürr, P., Grillari-Voglauer, R., Brunner, S., Trajanoski, Z.   +27 more
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MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells [PDF]

Oncogene, 2013
miRNAs act as oncogenes or tumor suppressors in a wide variety of human cancers, including prostate cancer (PCa). We found a severe and consistent downregulation of miRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 region in metastatic cell lines as compared with ...
Formosa, A, Markert, E, LENA, ANNA MARIA, Italiano, D, FINAZZI AGRO', ENRICO, Levine, A, BERNARDINI, SERGIO, Garabadgiu, A, MELINO, GENNARO, Candi, E.   +9 more
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Expression of microRNAs, miR‐21, miR‐31, miR‐122, miR‐145, miR‐146a, miR‐200c, miR‐221, miR‐222, and miR‐223 in patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma and its prognostic significance

Molecular Carcinogenesis, 2011
AbstractMicroRNAs are a class of non‐coding molecules found to regulate a variety of cellular functions in health and disease. Dysregulation of microRNAs is involved in liver disease, especially hepatocarcinogenesis. Since primary hepatic malignancies are typically characterized by late diagnosis, frequent recurrence, and poor response to adjuvant ...
Karakatsanis, A., Papaconstantinou, I., Gazouli, M., Lyberopoulou, A., Polymeneas, G., Voros, D.   +5 more
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Does Neuroticism Disrupt the Psychological Benefits of Nostalgia? A Meta‐analytic Test

European Journal of Personality, EarlyView., 2020
Abstract Nostalgia, a sentimental longing or wistful affection for the past, confers self‐oriented, existential, and social benefits. We examined whether nostalgic engagement is less beneficial for individuals who are high in neuroticism (i.e. emotionally unstable and prone to negative affect).
Julius Frankenbach, Tim Wildschut, Jacob Juhl, Constantine Sedikides, Odilia Laceulle   +4 more
wiley   +1 more source

Microvesicle-associated and circulating microRNAs in diabetic dyslipidemia: miR-218, miR-132, miR-143, and miR-21, miR-122, miR-155 have biomarker potential

Cardiovascular Diabetology, 2023
Abstract Background Circulating MicroRNAs (miRNAs) carried by microvesicles (MVs) have various physiological and pathological functions by post-transcriptional regulation of gene expression being considered markers for many diseases including diabetes and dyslipidemia.
Miruna Nemecz, Diana Simona Stefan, Ioana Karla Comarița, Alina Constantin, Gabriela Tanko, Cristian Guja, Adriana Georgescu   +6 more
openaire   +3 more sources