Results 11 to 20 of about 180 (179)
Advances in Molecular Oncology, 2022 Introduction. Testicular germ cell tumor is a relatively rare disease. Its high social significance is due to the fact that this pathology occurs in young patients. The standard schemes of polychemotherapy determine the potential possibility of effective treatment for most of the patients even with an advanced disease.
M. S. Knyazeva +10 more
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Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer [PDF]
BMC Cancer, 2012 MicroRNAs (miRNAs) regulate gene expression by binding to mRNA, and can function as oncogenes or tumor suppressors depending on the target. In this study, using qRT-PCR, we examined the expression of six miRNAs (miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145) in tumors from 193 prospectively recruited patients with colorectal cancer, and ...
Schee Kristina +4 more
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FAIM Is Regulated by MiR-206, MiR-1-3p and MiR-133b [PDF]
Frontiers in Cell and Developmental Biology, 2020 Apoptosis plays an important role during development, control of tissue homeostasis and in pathological contexts. Apoptosis is executed mainly through the intrinsic pathway or the death receptor pathway, i.e., extrinsic pathway. These processes are tightly controlled by positive and negative regulators that dictate pro- or anti-apoptotic death receptor
Elena Coccia +13 more
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miR-1, miR-10b, miR-155, and miR-191 are novel regulators of BDNF [PDF]
Cellular and Molecular Life Sciences, 2014 Brain-derived neurotrophic factor (BDNF) is a secreted protein of the neurotrophin family that regulates brain development, synaptogenesis, memory and learning, as well as development of peripheral organs, such as angiogenesis in the heart and postnatal growth and repair of skeletal muscle.
Varendi, Kärt +3 more
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Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients [PDF]
British Journal of Cancer, 2015 Owing to late diagnosis in advanced disease stages, prognosis of patients with epithelial ovarian cancer (EOC) is poor. The quantification of deregulated levels of microRNAs could facilitate earlier diagnosis and improve prognosis of EOC.Seven microRNAs (miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429) were quantified in the serum of 180 ...
Xiaodan Meng +8 more
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miR‐17, miR‐19b, miR‐20a, and miR‐106a are down‐regulated in human aging [PDF]
Aging Cell, 2010 SummaryAging is a multifactorial process where deterioration of body functions is driven by stochastic damage while counteracted by distinct genetically encoded repair systems. To better understand the genetic component of aging, many studies have addressed the gene and protein expression profiles of various aging model systems engaging different ...
Hackl, Matthias +27 more
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Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients [PDF]
Journal of Translational Medicine, 2013 Abstract Background Glioblastoma multiforme (GBM) is the most common and aggressive brain tumor with poor clinical outcome. Identification and development of new markers could be beneficial for the diagnosis and prognosis of GBM patients. Deregulation of microRNAs (miRNAs or miRs) is involved in GBM.
Qiu, Shuwei +5 more
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Genetic Variants miR-126, miR-146a, miR-196a2, and miR-499 in Polycystic Ovary Syndrome [PDF]
British Journal of Biomedical Science, 2022 Introduction: Alterations in certain microRNAs (miRNAs) and their target genes have reported in polycystic ovary syndrome (PCOS) and other disease of the female reproductive system, and so may be potential biomarkers. We hypothesised alterations in the prevalence of four miRNAs single nucleotide polymorphism (SNP) variants miR-126 rs4636297, miR-146a ...
Li, R. +6 more
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Does Neuroticism Disrupt the Psychological Benefits of Nostalgia? A Meta‐analytic Test
European Journal of Personality, EarlyView., 2020 Abstract Nostalgia, a sentimental longing or wistful affection for the past, confers self‐oriented, existential, and social benefits. We examined whether nostalgic engagement is less beneficial for individuals who are high in neuroticism (i.e. emotionally unstable and prone to negative affect).
Julius Frankenbach +4 more
wiley +1 more source
MiR-574-5P, miR-1827, And miR-4429 As Potential Biomarkers For Schizophrenia [PDF]
Journal of Molecular Neuroscience, 2021 Abstract Schizophrenia is a severe chronic debilitating disorder with millions of affected individuals. Lack of a reliable mollecular diagnostic invokes the identification of novel biomarkers. To elucidate the molecular basis of the disease, two mRNA expression arrays including GSE93987 and GSE38485, and one miRNA array, GSE54914, were ...
Omran Davarinejad +7 more
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