Results 361 to 370 of about 563,981 (384)
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2016
MicroRNAs (miRNAs) are small, highly conserved noncoding RNA molecules involved in the regulation of gene expression. Since each miRNA regulates the expression of hundreds of target mRNAs, miRNAs could function as master coordinators, efficiently regulating fundamental cellular processes, including proliferation, apoptosis, and development. Furthermore,
Lu, Gao, Feng, Jiang
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MicroRNAs (miRNAs) are small, highly conserved noncoding RNA molecules involved in the regulation of gene expression. Since each miRNA regulates the expression of hundreds of target mRNAs, miRNAs could function as master coordinators, efficiently regulating fundamental cellular processes, including proliferation, apoptosis, and development. Furthermore,
Lu, Gao, Feng, Jiang
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miRNAs Targeting and Targeting miRNAs
2009With the recent advance of research into microRNAs (miRNAs), this category of endogenous noncoding small ribonucleic acids (19–25 nts in length) has rapidly emerged as one of the central regulators of expression of an extensive repertoire of genes. MiRNAs are an abundant RNA species constituting >2% of the predicted human genes (> 1,000 genes), which ...
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Science, 2017
Small RNA Decay Although much work has examined microRNA (miRNA) biogenesis, relatively little is known about miRNA decay. Elbarbary et al. now identify Tudor-SN, an endonuclease that interacts with the RNA-induced silencing complex. Tudor-SN targets miRNAs at CA and UA dinucleotides located more than five nucleotides from miRNA ends. Tudor–SN-mediated
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Small RNA Decay Although much work has examined microRNA (miRNA) biogenesis, relatively little is known about miRNA decay. Elbarbary et al. now identify Tudor-SN, an endonuclease that interacts with the RNA-induced silencing complex. Tudor-SN targets miRNAs at CA and UA dinucleotides located more than five nucleotides from miRNA ends. Tudor–SN-mediated
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MiRNAs: Biology, Biogenesis, their Web-based Tools, and Databases.
MicroRNA, 2018INTRODUCTION MicroRNAs (miRNAs), which are evolutionarily conserved, and endogenous non-coding RNAs, participate in the post-transcriptional regulation of eukaryotic genes. The biogenesis of miRNAs occurs in the nucleus.
Majid Tafrihi, Elham Hasheminasab
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Life Sciences, 2011
Despite significant advances in treatments, cardiovascular disease (CVD) remains the leading cause of human morbidity and mortality in developed countries. The development of novel and efficient treatment strategies requires an understanding of the basic molecular mechanisms underlying cardiac function.
Terry S, Elton +5 more
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Despite significant advances in treatments, cardiovascular disease (CVD) remains the leading cause of human morbidity and mortality in developed countries. The development of novel and efficient treatment strategies requires an understanding of the basic molecular mechanisms underlying cardiac function.
Terry S, Elton +5 more
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Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011
The Epstein-Barr virus (EBV) is an oncogenic Herpes virus involved in the induction of a variety of human tumours. It was the first virus found to encode microRNAs (miRNAs). MiRNAs are short, non-coding RNAs that in most cases negatively regulate gene expression at the post-transcriptional level.
Stephanie, Barth +2 more
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The Epstein-Barr virus (EBV) is an oncogenic Herpes virus involved in the induction of a variety of human tumours. It was the first virus found to encode microRNAs (miRNAs). MiRNAs are short, non-coding RNAs that in most cases negatively regulate gene expression at the post-transcriptional level.
Stephanie, Barth +2 more
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NTP4 modulates miRNA accumulation via asymmetric modification of miRNA/miRNA* duplex
Science China Life Sciences, 2020Wenwen, Kong +7 more
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Cancer-associated miRNAs and their therapeutic potential
Journal of Human Genetics, 2021J. Inoue, J. Inazawa
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