Results 51 to 60 of about 673,088 (264)

Mirror-touch synesthesia in schizophrenia, a pathological condition?

Debates em Psiquiatria, 2022
Introduction: The mirror-touch synesthesia is a condition where a touch perception in another person's body induces the person who is observed to feel being touched in the same way.
César Augusto Trinta Weber, Mario Francisco Pereira Juruena   +1 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Acquisition of automatic imitation is sensitive to sensorimotor contingency [PDF]

, 2010
The associative sequence learning model proposes that the development of the mirror system depends on the same mechanisms of associative learning that mediate Pavlovian and instrumental conditioning. To test this model, two experiments used the reduction
Heyes, C., Press, C., Heyes, Cecelia, Press, C, Heyes, C, Cook, R, Press, Clare Mary, Cecilia Heyes, Heyes, Cecilia, Dickinson, A., Richard Cook, Clare Press, Anthony Dickinson, Cook, R., Press, Clare, Cook, Richard, Dickinson, A, Dickinson, Anthony   +17 more
core   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

(Mis)understanding mirror neurons [PDF]

, 2010
SummaryIt is hard to imagine a class of neurons that has generated more excitement than mirror neurons, cells discovered by Rizzolatti and colleagues [1] in macaque area F5 that fire both during action execution and action observation.
Hickok, Gregory, Marc Hauser, Hauser, Marc, Gregory Hickok   +3 more
core   +1 more source

The role of mirror neurons in empathy, with a focus on their relevance in autism spectrum disorder and other clinical implications

Journal of Education, Health and Sport
Introduction Mirror neurons are brain cells that engage when an individual performs an action and then observes another person completing the same action.
Weronika Kiełt, Julia Kozłowska, Gabriela Broniec, Barbara Wajdowicz, Aleksandra Kudła, Rozalia Czapiewska, Aleksandra Dziewulska, Aleksandra Wróbel, Laura Pacek, Klaudia Kowalska   +9 more
doaj   +1 more source

View-Invariant Visuomotor Processing in Computational Mirror Neuron System for Humanoid.

PLoS ONE, 2016
Mirror neurons are visuo-motor neurons found in primates and thought to be significant for imitation learning. The proposition that mirror neurons result from associative learning while the neonate observes his own actions has received noteworthy ...
Farhan Dawood, Chu Kiong Loo
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Why our brains cherish humanity: Mirror neurons and colamus humanitatem

Avances en Psicología Latinoamericana, 2008
Commonsense says we are isolated. After all, our bodies are physically separate. But Seneca’s colamus humanitatem, and John Donne’s observation that “no man is an island” suggests we are neither entirely isolated nor separate.
John R. Skoyles
doaj